Secondary prevention of sudden cardiac death

Chatterjee, Neal A.; Rea, Thomas D.

doi:10.1016/j.hroo.2020.08.002

Cited by 4 publications

(9 citation statements)

References 83 publications

(148 reference statements)

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“…SCD accounts for 15-20% of mortality globally and is frequently caused by ventricular arrythmias. In the Western world, coronary ischemia is the underlying cause of ventricular arrhythmias leading to 50% of SCD events [ 1 ]. ICD therapy is recommended for secondary prevention per guidelines for those who have survived cardiac arrest attributable to VT, VF, or those who have sustained VT not due to a reversible cause and have greater than a one-year life expectancy [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

“…Sudden cardiac death (SCD) accounts for 15-20% of mortality globally and is frequently caused by ventricular arrhythmias [ 1 ]. In the Western world, coronary heart disease is the underlying cause of ventricular arrhythmias leading to SCD.…”

Section: Introductionmentioning

confidence: 99%

“…In the Western world, coronary heart disease is the underlying cause of ventricular arrhythmias leading to SCD. Implantable cardioverter-defibrillator (ICD) is recommended per guidelines for those who have survived cardiac arrest attributable to ventricular tachycardia (VT), ventricular fibrillation (VF), or those who have sustained VT not due to a reversible cause and have greater than a one-year life expectancy [ 1 ]. Three landmark randomized clinical trials Cardiac Arrest Study Hamburg (CASH), Anti-arrhythmic Versus Implantable Defibrillator (AVID), and Canadian Implantable Defibrillator Study (CIDS) evaluating the efficacy of ICD therapy thus far have shown that ICD is highly effective, well tolerated, and cost-effective when compared with conventional drug therapy [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The Plumber Versus Electrician Dilemma: To Bypass or to Defibrillate?

Singu,

Dearing,

Robichaux, Jr.

et al. 2024

Cureus

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We present a unique case of an 80-year-old male who presented to our emergency department following cardiac defibrillation when he was found to be in polymorphic ventricular tachycardia (VT) after a syncopal event while at cardiac rehabilitation. He had known coronary artery disease and had a four-vessel coronary artery bypass graft (CABG) 20 years prior to presentation. He underwent left heart catheterization (LHC) two months prior to the syncopal event for worsening shortness of breath and the decision at that time was to proceed with medical management and intervene with redo-CABG if shortness of breath did not improve or progressively worsened. While admitted under our care after the polymorphic VT event, we faced the dilemma of whether to proceed with redo-CABG first since cardiac ischemia is a common cause of polymorphic VT or whether to insert an implantable cardioverter-defibrillator (ICD) before proceeding with redo-CABG. We present the current literature that addresses ICD implantation for secondary prevention and our approach to this complicated case.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Plumber Versus Electrician Dilemma: To Bypass or to Defibrillate?

Singu,

Dearing,

Robichaux, Jr.

et al. 2024

Cureus

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“…Future prospective studies evaluating ECG features, ventricular arrhythmia burden and morphology, and electrophysiological findings may provide further information. In individuals with different MAD phenotypes, further evidence could clarify its arrhythmogenic role and specify the effectiveness of antiarrhythmic therapy, the potential use of early catheter ablation in refractory ventricular arrhythmias, and the surgical approach in managing ventricular arrhythmia in patients with MVP ( 32 ).…”

Section: Discussionmentioning

confidence: 99%

Case report: Aborted sudden cardiac death as a first presentation of severe mitral annulus disjunction—a case series and review of the literature

Apostolou

Ioannides

Mitsis

et al. 2023

Front. Cardiovasc. Med.

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Mitral annulus disjunction (MAD) is defined as a systolic displacement between the ventricular myocardium and the posterior mitral annulus supporting the posterior mitral leaflet. This structural abnormality is associated with the loss of mechanical annular function manifested as an abnormal systolic excursion of the leaflet hinge point into the left atrium but with maintained electrical function, separating the left atrium and ventricle electrophysiologically. The mitro-aortic fibrous continuity limits MAD anteriorly, between the aortic cusps and the anterior leaflet of the mitral valve. Consequently, MAD has been observed only at the insertion of the posterior leaflet. It can extend preferentially at the central posterior scallop. The first diagnostic modality aiding the diagnosis is transthoracic echocardiography (TTE), although in some cases adjunctive cardiac imaging modality might be suggested. MAD carries a strong association with malignant ventricular arrhythmogenesis and a profound predisposition for sudden cardiac death (SCD). In this context, a thorough investigation of this morphological and functional abnormality is vital in estimating the risk assessment and stratification for optimal management and elimination of the risk of the patient for SCD. Based on the current scientific data and literature, we will discuss the diagnosis, clinical implications, risk stratification, and therapeutic management of MAD.

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“…However, a meta-analysis of these three milestone randomized trials suggests that the preventive effect of ICDs existed only in patients with an LVEF ≤35%. Furthermore, ICD implantation can result in potentially fatal complications such as recurrent and persistent VT/VF [22].…”

Section: Secondary Preventionmentioning

confidence: 99%

Sudden cardiac death in patients with myocardial infarction: 1.5 primary prevention

Feng¹,

Feng²

2021

Reviews in Cardiovascular Medicine

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Sudden cardiac death (SCD) is one of the most common causes of death in the world. Coronary heart disease (CHD) is the root cause of most patients with SCD, and myocardial infarction (MI) is the main cause of SCD among all types of CHD. Early identification of high-risk patients after an MI, and the application of related prevention strategies and disease-specific treatments will be the key to reduce SCD. The mechanism of SCD after MI varies over time, and the relevant risk prediction indicators are also dynamic and different. In the existing guidelines for MI patients, the static and slightly single stratification of primary (PP) and secondary (SP) prevention has significant room for improvement. The 1.5 primary prevention (1.5PP) is defined as patients with PP who also had the following risk factors: non-sustained ventricular tachycardia (NSVT), frequent premature ventricular contractions (PVCs), severe heart failure (left ventricular ejection fraction, LVEF <25%), and syncope or pre-syncope. The emergence of 1.5PP has provided a new method for the stratification and management of SCD after an MI.

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Secondary prevention of sudden cardiac death

Cited by 4 publications

References 83 publications

The Plumber Versus Electrician Dilemma: To Bypass or to Defibrillate?

The Plumber Versus Electrician Dilemma: To Bypass or to Defibrillate?

Case report: Aborted sudden cardiac death as a first presentation of severe mitral annulus disjunction—a case series and review of the literature

Sudden cardiac death in patients with myocardial infarction: 1.5 primary prevention

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