Secondary metabolites of Seseli rigidum: Chemical composition plus antioxidant, antimicrobial and cholinesterase inhibition activity

Stаnkov-Jovаnović, Vesnа; Ilić, Marija; Mitić, Violeta; Mihajilov‐Krstev, Tatjana; Simonović, Strahinja R.; Nikolic-Mandic, Snezana; Tabet, Jean‐Claude; Cole, Richard B.

doi:10.1016/j.jpba.2015.03.015

Cited by 17 publications

(16 citation statements)

References 20 publications

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“…Other Seseli species, however, had quite different root essential oils as S. pallasii with nonane (45.2 %), (Z)-β-ocimene (34.5 %) and undecane (13.3 %). [29] S. rigidum [30,31] and S. gracile [32] had falcarinol or falcarinol and octanol as main components in their root essential oils.…”

Section: Resultsmentioning

confidence: 99%

Chemodiversity of Essential Oils in Seseli libanotis (L.) W.D.J.Koch (Apiaceae) in Central Europe

Chizzola

2019

Chemistry & Biodiversity

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Seseli libanotis is an aromatic umbelliferous plant distributed sporadically on dry grassland edges in Europe and Western Asia. The essential oil composition in the different plant parts was studied from plants collected on nine sites in Austria and one site in Alto Adige, Italy. Monoterpenes such as α‐pinene, sabinene and β‐myrcene and the sesquiterpene germacrene D were present in all essential oils from the aerial parts. Inflorescences and fruits had the highest essential oil contents. These essential oils from four sites were rich in acorenone B, while from other three sites they had carotol as a major component. Osthole as furocoumarin occurred in some oils. The root essential oils were dominated by α‐pinene. The essential oil variability has been studied by principal component analysis (PCA) and discriminant analysis (DA) with plant parts or sampling site as a priori groups. PCA could well separate inflorescence and fruit essential oil samples from leaf and stem essential oil samples. DA differentiated well between the plant parts and most of the sampling sites.

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Section: Resultsmentioning

confidence: 99%

Chemodiversity of Essential Oils in Seseli libanotis (L.) W.D.J.Koch (Apiaceae) in Central Europe

Chizzola

2019

Chemistry & Biodiversity

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“…EOs isolated from the aerial parts of different Seseli species did not exhibit significant antioxidant potential 24,26 . Chemical analysis of S. gracile EO showed γ-terpinene and terpinolene were the most abundant components, representing 63.89% of total oil 17 EOs components demonstrated that γ-terpinene and terpinolene had a very similar radicalscavenging effect but much stronger than that of a Trolox (referent antioxidant substance).…”

Section: Antioxidant Activity (Dpph Radical Assay)mentioning

confidence: 88%

“…rigidum 21 , S. campestre 22 and S. tortuosum 23 as well as from S. rigidum fruit 24 . Moreover, in abovementioned EOs monoterpenes were mostly represented with α-pinene (35.9-57.4%).…”

Section: Discussionmentioning

confidence: 99%

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Pharmacological characterisation of Seseli gracile Waldst. & Kit (Apiaceae) essential oil

et al. 2021

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Background/Aim. Phytochemical and pharmacological investigations of essential oils isolated from plant species of the genus Seseli have been intensified recently. These plant species have long-term use in nutrition and traditional medicine in the treatment of various disorders. Volatile secondary metabolites of Seseli gracile Waldst. & Kit (Apiaceae) have not been pharmacologically examined so far. The aim of the conducted research was to assess the antiradical, antimicrobial and spasmolytic activities of S. gracile essential oil isolated from the aerial parts of the plant. Methods. The antiradical activity was determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging test, antimicrobial activity using broth microdilution method with standard strains of Gram (+), Gram (-) bacteria and yeast, while spasmolytic activity was evaluated on isolated rat ileum, pre-contracted with a high concentration of potassium. Results. The results showed moderate antiradical (SC50 = 78,60 µg/mL) and good spasmolytic activity (IC50 = 271.4 nL/mL) of S. gracile essential oil. In the range of tested concentrations, minimal inhibitory concentration (MIC) was determined only for the strain of Escherichia coli (500 μg/ml). Conclusion. Results obtained in this study justify the need for further studies to elucidate exact molecular mechanism underlay this spasmolytic effect of S. gracile herb essential oil.

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“…GC-MS/MS analysis was used to identify compounds in the extracted Acacia seyal gum (ASG), in accordance with the method reported by Stankov-Jovanović et al [49]. The analysis was carried out using a GC (from Agilent Technologies 7890A) interfaced with a mass-selective detector (MSD) (Agilent 7000 Triple Quad).…”

Section: Gc-ms/ms Analysismentioning

confidence: 99%

Gum arabic: an optimization of ultrasonic- assisted extraction of antioxidant activity

Elnour¹,

Mirghani²,

Kabbashi³

et al. 2018

Studia UBB Chemia

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Gum Arabic (GA), also known as Acacia seyal gum (ASG), is a dried exudate from trees of Acacia senegal and Acacia seyal. It provides a rich source of non-viscous soluble fiber with significant health benefits and high antioxidant properties. Tonnes of raw GA are exported annually at a high cost with limited utilization in extraction form. Techniques for the extraction of the bioactive components of GA are available but the high extraction time and the capacity and quality of extraction hinders these procedures. Ultrasonicassisted extraction is one of the most effective techniques for the recovery of antioxidant and phenolic compounds from ASG. A comparatively low extraction time has been reported for ultrasonication, but the influence of several extraction conditions such as temperature, time and ultrasonic power on the yield of extraction has not been thoroughly studied. This study investigates the optimal ultrasonic extraction conditions for maximum recovery of antioxidant and phenolic compounds from ASG using Response Surface Methodology (RSM) under the Central Composite Design (CCD). Three ultrasonic parameters, namely time in the range of (1-3 hours), power in the range of (1-3 level or 12 to 40 kHz) and temperature from (25-60 °C) were tested for their impact on antioxidant activity. The capacity of the extracts was determined by the scavenging activity of 1, 1-diphenyl-2picrylhydrazyl (DPPH) radical, ferric reducing antioxidant power (FRAP) assay, and total phenolic compounds (TPC). The results indicated that ultrasonic time, power and temperature had a positive impact on antioxidant capacity and phenolic compounds. The optimum ultrasonic conditions were

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Secondary metabolites of Seseli rigidum: Chemical composition plus antioxidant, antimicrobial and cholinesterase inhibition activity

Cited by 17 publications

References 20 publications

Chemodiversity of Essential Oils in Seseli libanotis (L.) W.D.J.Koch (Apiaceae) in Central Europe

Chemodiversity of Essential Oils in Seseli libanotis (L.) W.D.J.Koch (Apiaceae) in Central Europe

Pharmacological characterisation of Seseli gracile Waldst. & Kit (Apiaceae) essential oil

Gum arabic: an optimization of ultrasonic- assisted extraction of antioxidant activity

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