Secondary metabolites of rice sheath blight pathogen Rhizoctonia solani Kühn and their biological activities

Xu, Liang; Wang, Xiaohan; Luo, Ruiya; Lu, Shiqiong; Guo, Zhai; Wang, Mingan; Liu, Yang; Zhou, Ligang

doi:10.1016/s2095-3119(14)60905-9

Cited by 18 publications

(10 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Twenty-two known analogous (7-28) were identified by analysis of their spectroscopic data with the reported data for xuetongsu (schisanlactone E, 7) 10.8 g (Liu and Huang, 1991), kadnanolactone A (8) 5.0 mg (Yang et al, 2010), schisanlactone B (9) 25.0 mg (Liu et al, 1983), kadsuphilactone B (10) 6.8 mg (Shen et al, 2005), schisanbilactone A (11) 4.0 mg (Ma et al, 2009), cycloartenone (12) 2.5 g (Pavanasisivam and Sultanbawa, 1973), schisandronic acid (13) 18.2 mg (Li et al, 2003), heteroclic acid (14) 5.6 mg (Wang et al, 2006b), changnanic acid (15) 18.0 mg (Liu and Huang, 1991), heteroclitalactone C (16) 5.5 mg (Wang et al, 2006b), heteroclitalactone D (17) 42.0 mg (Wang et al, 2006b), heteroclitalactone F (18) 7.0 mg (Wang et al, 2006b), heteroclitalactone G (19) 22.0 mg (Wang et al, 2007), heteroclitalactone I (20) 6.5 mg (Wang et al, 2007), heteroclitalactone K (21) 12.5 mg (Wang et al, 2007), heteroclitalactone L (22) 15.3 mg (Wang et al, 2007), heteroclitalactone M (23) 17.3 mg (Wang et al, 2007), sorghumol (24) 12.9 mg (Han et al, 2008), β-sitosterol (25) 100 mg (Chaturvedula and Prakash, 2012), daucosterol (26) 10.0 mg (Rahmana et al, 2009), 6β-hydoxysitostenone (27) 7.6 mg (Liang et al, 2015), and a steroid, trihydoxy pregnene (28) 13.0 mg (Deng et al, 2010). Their structures are presented in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

Xuetonglactones A–F: Highly Oxidized Lanostane and Cycloartane Triterpenoids From Kadsura heteroclita Roxb. Craib.

Shehla

Cao

et al. 2020

Front. Chem.

View full text Add to dashboard Cite

Xuetonglactones A-F (1-6), six unreported highly oxidized lanostane-and cycloartane-type triterpenoids along with 22 known scaffolds (7-28) were isolated from the stems of Kadsura heteroclita (Roxb.) Craib. Compared with previous congeners, xuetonglactone A (1), possesses an unprecedented 20,21-α-epoxide, and xuetonglactone D (4) features an unusual 19-α-hydroperoxyl moiety. The structures and the absolute configurations of the compounds were established by extensive one-and two-dimensional NMR, and electronic circular dichroism (ECD) spectroscopic analysis, with those of 1 and 5 confirmed by single-crystal X-ray diffraction technique. Compounds 1 and 2 exhibited inhibition of iNOS activity in LPS-induced macrophages with IC 50 values of 22.0, and 17.0 µg/mL, respectively. While compounds 6, 7, 8, and 24 showed potent cytotoxic activities against human cervical cancer cell lines (HeLa) with the IC 50 values of 4.0, 5.8, 5.0, and 6.4 µM, and against human gastric cancer cells (BGC 823) with the IC 50 values of 2.0, 5.0, 2.5, and 2.0 µM, respectively. Moreover, plausible biogenetic pathways of (1-6) were also proposed.

show abstract

Section: Resultsmentioning

confidence: 99%

Xuetonglactones A–F: Highly Oxidized Lanostane and Cycloartane Triterpenoids From Kadsura heteroclita Roxb. Craib.

Shehla

Cao

et al. 2020

Front. Chem.

View full text Add to dashboard Cite

show abstract

“…Previous research has shown that R. solani also produces phenyl acetic acid and its derivatives (Bartz et al, 2013 ), a phenolic compound, and a carbohydrate as phytotoxins that supported the broad host range and diversity within the R. solani species. Xu et al ( 2015 ) identified eight compounds from fermentation broth of R. solani , from which m -hydroxymethylphenyl pentanoate, (Z)-3-methylpent-2-en-1,5-dioic acid and 3-methoxyfuran-2-carboxylic acid showed phytotoxicity in vitro .…”

Section: Phytotoxins Phytoalexins and Special Smsmentioning

confidence: 99%

Secondary metabolites in fungus-plant interactions

2015

View full text Add to dashboard Cite

Fungi and plants are rich sources of thousands of secondary metabolites. The genetically coded possibilities for secondary metabolite production, the stimuli of the production, and the special phytotoxins basically determine the microscopic fungi-host plant interactions and the pathogenic lifestyle of fungi. The review introduces plant secondary metabolites usually with antifungal effect as well as the importance of signaling molecules in induced systemic resistance and systemic acquired resistance processes. The review also concerns the mimicking of plant effector molecules like auxins, gibberellins and abscisic acid by fungal secondary metabolites that modulate plant growth or even can subvert the plant defense responses such as programmed cell death to gain nutrients for fungal growth and colonization. It also looks through the special secondary metabolite production and host selective toxins of some significant fungal pathogens and the plant response in form of phytoalexin production. New results coming from genome and transcriptional analyses in context of selected fungal pathogens and their hosts are also discussed.

show abstract

“…The extracted toxins from R. oryzae-sativae had a stronger inhibitory effect on rice radicle (Table 3). Studies indicate that the biological ability of toxins from different strains was significantly different (Ren et al, 2017;Xu et al, 2015). The pathogenicity of strains is positively correlated with the activity of toxins, and the sensitivity of different hosts to toxins are also different.…”

Section: Discussionmentioning

confidence: 99%

“…The radicle length of each seed was measured. The elongation inhibitory rate of the radicle was determined by using the method of Xu D r a f t 6 et al (Xu et al, 2015). The experiment has been replicated twice.…”

Section: Inhibitory Activity Assaymentioning

confidence: 99%

Phytotoxin of rice aggregate sheath spot pathogen Rhizoctonia oryzae-sativae and its biological activities

Wang¹,

Ai-min²,

Chen

et al. 2021

Can. J. Microbiol.

View full text Add to dashboard Cite

Rice aggregate sheath spot disease occurs in many countries, causing serious yield losses. In China, the disease-causing fungus Rhizoctonia oryzae-sativae was reported in 1985, and since then, it has rarely been reported in major rice-growing areas after almost 30 years. Compared with Rhizoctonia solani, R. oryzae-sativae has a significantly different physiological morphology and growth status, although both fungi affect rice leaves in very similar ways. The optimum temperature for the suitable growth of R. oryzae-sativae is 31 °C, which is consistent with previous reports. We extracted phytotoxins from R. oryzae-sativae and analyzed its biological activity via the detached leaf and radicle inhibition methods. Rhizoctonia solani and R. oryzae-sativae exhibit differences in terms of pathogenicity and toxins activity, which indicates that these fungi may produce different toxins components. Based on gas chromatography–mass spectrometry data, esters, phenols, and other components were present in the crude toxins extract of R. oryzae-sativae. Our research provides a new method for studying the phytotoxins of R. oryzae-sativae. However, further studies are needed to elucidate the pathogenic mechanisms responsible for the aggregate sheath spot disease on rice.

show abstract

Secondary metabolites of rice sheath blight pathogen Rhizoctonia solani Kühn and their biological activities

Cited by 18 publications

References 23 publications

Xuetonglactones A–F: Highly Oxidized Lanostane and Cycloartane Triterpenoids From Kadsura heteroclita Roxb. Craib.

Xuetonglactones A–F: Highly Oxidized Lanostane and Cycloartane Triterpenoids From Kadsura heteroclita Roxb. Craib.

Secondary metabolites in fungus-plant interactions

Phytotoxin of rice aggregate sheath spot pathogen Rhizoctonia oryzae-sativae and its biological activities

Contact Info

Product

Resources

About