Secondary Metabolites From Probiotic Metabolism

Chávarri, Marı́a; Diez-Gutiérrez, Lucía; Marañón, Izaskun; Barrón, Luis Javier R.

doi:10.1016/b978-0-12-822909-5.00017-4

Cited by 11 publications

(8 citation statements)

References 119 publications

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“…Mechanisms frequently observed in most probiotic strains. Examples: vitamin synthesis (Chávarri et al., 2021; Khromova et al., 2022), regulation of bile salt metabolism (Bourgin et al., 2021; Gadaleta et al., 2022), strengthening of the intestinal barrier (Camilleri, 2021; di Vito et al., 2022; Guo et al., 2022), provides enzyme activity (Olivares et al., 2006; Pavlović et al., 2012) and neutralization of carcinogens (Burns & Rowland, 2000). Rare mechanisms present in only a few strains of a given species.…”

Section: Addition Of Dietary Supplements—diversification Of Functions...mentioning

confidence: 99%

From the past to the future: Fermented milks and their health effects against human diseases

Zhang,

Geng,

Cheng

et al. 2023

Food Frontiers

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The benefits of fermented milk have been known to mankind since the ancient days of civilization. The important role of fermented milk in human nutrition has been well documented through the ages, from the original unpredictable souring of milk caused by the microorganisms inherent in milk to modern microbiological processes, leading to fermented milk with the greater nutritional value produced under controlled conditions. The bioactive peptides synthesized by the microbial degradation of proteins in fermented milk and the addition of supplements, such as probiotics and prebiotics endow them with various physiological functions, including the regulation of the gut microbiota, cholesterol lowering, and immunomodulation, making them potential functional foods that are notable in healthy diets. Here, we summarized the development of fermented milk into four stages and also summarized their impact on health and diseases during different developmental stages. In addition, we described the characteristics and limitations of fermented milk in different eras. Accordingly, we integrated the future trends in the development of fermented milk as functional foods. It is hoped that the efforts to develop the potential of fermented milk as functional foods will help manage the health risks faced by many countries.

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Section: Addition Of Dietary Supplements—diversification Of Functions...mentioning

confidence: 99%

From the past to the future: Fermented milks and their health effects against human diseases

Zhang,

Geng,

Cheng

et al. 2023

Food Frontiers

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“…Probiotic secondary metabolites, known as postbiotics, exhibit potential beneficial effects in humans like prevention or treatment of inflammatory diseases, diabetes, neurological disorders, etc. Among compounds described vitamins, amino acids, or antimicrobials are gaining great interest [75] . Anwar et al [76] revealed antiviral effects of probiotic metabolites on COVID-19 via a molecular dynamics study using metabolic product of Lactobacillus plantarum that blocks the entry by binding SARS-CoV-2.…”

Section: Immunobiotics Intervention In Gut-lung Pathwaysmentioning

confidence: 99%

Probiotics for immunomodulation in prevention against respiratory viral infections with special emphasis on COVID-19

Amrouche

Chikindas

2022

AIMSMICRO

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COVID-19 pandemic is currently causing high mortality and economic crisis, and several drugs-based therapeutic strategies and vaccines are unfortunately used with little efficiency. Therefore, here is an urgent need to provide additives therapies that prevent or improve symptoms in populations infected by SARS-CoV-2 variants. This review aimed to examine relevant scientific information related to SARS-CoV-2 and host antiviral immunity, as well the possible role of probiotics in gut-lung cross talk pathways to promote lung immune response to COVID-19 infection. We searched online databases such as PubMed, Embase, Chinese databases, and selected articles and studies with relevant data reported on COVID-19 and other respiratory viral infections. Recent research highlighted potential immunomodulatory activities of probiotics assessed in animal models and clinical trials. However, the role of probiotics and gut microbiome in COVID-19 management, and approaches with significant understanding in molecular mechanism of probiotic action remain poorly investigated. Clinical investigations as well as animal model studies published have demonstrated that probiotics such as Lactobacillus rhamnosus and Bifidumbacterium lactis HN019, may influence positively not only microbiota balance but also antiviral immunity by improving both innate and adaptive responses and controlling inflammatory reaction in respiratory viral infection. Given the immunological interactions in gut-lung axis and the crucial role of probiotics in modulating immune responses by promoting dendritic cells (DCs) to regulate T cell responses, we hypothesized that application of probiotics may be successful in prevention or treatment of both intestinal disorders and airway diseases in patients with COVID-19.

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“…For instance, it has been reported that the production of shortchain fatty acids from the metabolism of galactooligosaccharides improves the immune system promotes cell differentiation or maintains the intestinal microbiota (Fuhren et al, 2020;Tran et al, 2020). Moreover, the metabolism of amino acids, such as aspartic acid or tryptophan, could lead to the synthesis of essential human compounds, including hormones, nucleic acids or neurotransmitters (Chávarri, Diez-Gutiérrez, Marañón, & Barron, 2021).…”

Section: Introductionmentioning

confidence: 99%

Characterisation of the probiotic potential of Lactiplantibacillus plantarum K16 and its ability to produce the postbiotic metabolite γ-aminobutyric acid

Diez-Gutiérrez

Vicente

Sáenz

et al. 2022

Journal of Functional Foods

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Secondary Metabolites From Probiotic Metabolism

Cited by 11 publications

References 119 publications

From the past to the future: Fermented milks and their health effects against human diseases

From the past to the future: Fermented milks and their health effects against human diseases

Probiotics for immunomodulation in prevention against respiratory viral infections with special emphasis on COVID-19

Characterisation of the probiotic potential of Lactiplantibacillus plantarum K16 and its ability to produce the postbiotic metabolite γ-aminobutyric acid

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