Secondary malignancies diagnosed using kidney needle core biopsies: a clinical and pathological study of 75 cases

Left renal mass presenting uncommon pattern of extension in a patient with intestinal malrotation

“…Although there are a few cases showing unusual pattern of extension [8], none of these cases showed renal involvement, presumably because those cases had relatively early-stage diseases. The frequency of colon cancer invasion or metastasis to the kidney was reported as only 0-2.7% [9][10][11]. Involvement of the kidney as the first manifestation of primary colon cancer is an even rarer event [9].…”

Kidney Cancer Research Network of Canada (KCRNC) consensus statement on the role of renal mass biopsy in the management of kidney cancer

“…Lymphoma is rarely the cause of a solitary renal mass, however, it is the most common hematological malignancy to appear in a kidney. 41 Renal involvement of lymphoma can vary in appearance from multifocal, ill-defined, hypovascular lesions of different sizes to an infiltrative mass extending from the retroperitoneum with or without lymphadenopathy. 42 Finally, patients with a history of a concurrent or prior non-RCC malignancy must also be evaluated for the possibility of a metastatic deposit.…”

“…Solitary metastatic lesions are rarely present in the kidney, but have been reported from melanoma, lung cancer, colon cancer, and thyroid cancer. 41 When there is a concern that a renal mass could represent a pathology other than RCC, a renal mass biopsy should be considered.…”

Urologic Diseases Germane to the Medical Renal Biopsy: Review of a Large Diagnostic Experience in the Context of the Renal Architecture and Its Environs

“…With a metastasis a history of a nonrenal primary will usually be present as a renal presentation for a carcinoma primary elsewhere is very uncommon. 91 – 93 Most clinically detected renal metastases are solitary and unilateral, mimicking a renal primary. The time between diagnosis of the primary and detection of a renal metastasis may be as long as 5 to 10 years.…”

“…Lung, ear, nose and throat, and gastrointestinal tumors are the most common solid malignancies reported but many other primary sites may be seen. 91 – 93 The most common RCCs and many metastatic tumors may have a distinctive histology allowing definitive diagnosis. Desmoplasia is a common finding with a metastasis but also occurs with collecting duct carcinoma and when urothelial carcinoma extends into the kidney (Fig.…”