Secondary Intraocular Lens Implantation (IOL) in Children- What, Why, When, and How?

Lalwani, Sakshi; Kekunnaya, Ramesh

doi:10.1080/08820538.2022.2116288

Cited by 3 publications

(2 citation statements)

References 35 publications

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“…The optimum age for placing a secondary IOL in pediatric patients remains a subject of debate. 13 In the current series, the decision whether to place an IOL or leave the eye aphakic was, in general, age dependent. The younger patients (Case 1 and Case 4) were rendered aphakic despite having different surgical modalities and surgeons.…”

Section: Discussionmentioning

confidence: 76%

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Autosomal Recessive ADAMTSL4-Related Isolated Ectopia Lentis in the Ohio Old Order Amish and Mennonite Communities

Chiang,

Kloosterboer,

Örge

et al. 2024

Journal of VitreoRetinal Diseases

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Purpose: To present a series of 4 patients from the Ohio Amish or Mennonite populations with isolated ectopia lentis. Methods: A case series was evaluated. Results: Four cases with bilateral lens subluxations were diagnosed with a homozygous c.767_786del pathogenic variant in ADAMTSL4. Their ages ranged from 2 to 22 years. Three cases were symptomatic and were managed surgically with lensectomy, vitrectomy, and endolaser photocoagulation with or without secondary intraocular lens (IOL) implantation. One asymptomatic patient was observed. The postoperative visual acuity ranged from 20/20 to 20/60 in nonamblyopic eyes. Conclusions: The pathogenic homozygous c.767_786del variant in ADAMTSL4 may be a cause of bilateral isolated ectopia lentis in the Ohio Amish and Mennonite populations, likely as a result of a founder effect. Vitrectomy and lens extraction with or without secondary IOL implantation may lead to good visual outcomes. There were no cases of retinal detachment.

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Section: Discussionmentioning

confidence: 76%

“…14 Similarly, iris-fixated or anterior chamber IOLs can also result in endothelial cell loss over the long term. 13 The vitreoretinal considerations in our cases were also a priority. Two of the 4 cases had diffuse lattice degeneration or round atrophic holes with high degenerative myopia.…”

Section: Discussionmentioning

confidence: 85%