Secondary Hypertrophic Osteoarthropathy (Pierre Marie–bamberger Syndrome)

Крылов, А. С.; Щипахина, Я. А.; Фёдорова, А. В.; Ширяев, С. В.; Рыжков, А. Д.; Кочергина, Н. В.; Гончаров, М. О.; Неред, А. С.; Блудов, А. Б.

doi:10.20862/0042-4676-2017-98-5-251-255

Cited by 2 publications

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“…Использование гибридных и специализированных технологий. Создание и применение гибридных аппаратов ПЭТ-КТ, ОФЭКТ-КТ, ПЭТ-МРТ, ОФЭКТ-МРТ [1][2][3][4][5][6][7][8][9][10][11].…”

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Science research experience in the use of radiopharmaceuticals at the N.N. Petrov NMRC of Oncology

Krzhivitsky

2021

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Radionuclide diagnostics and therapy with open radionuclide sources are one of the most promising and fast-growing areas ofmodern oncology. The paper presents the main achievements of the N.N. Petrov National Medical Research Center of Oncology, one of the leading departments of radionuclide diagnostics in Russia. Scientific and clinical results of using the new hybrid device in everyday clinical practice have been submitted. The advantages and opportunities of using hybrid SPECT-CT and PET-CT devices to diagnose different types of cancer, to assess the degree of its spread and to monitor the results of therapy have been demonstrated. The problems associated with the demand for new radiopharmaceuticals in practice have been highlighted. The need to simplify normative documents regulating the use of modern therapeutic radionuclide drugs has been substantiated.

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Section: рис 1 офэкт-кт Fig 1 Spect-ctunclassified

Science research experience in the use of radiopharmaceuticals at the N.N. Petrov NMRC of Oncology

Krzhivitsky

2021

Pharmacy Formulas

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“…Особенно это актуально для пациентов старшего возраста, у которых переломы могут следствием различных дистрофических процессов, связанных со снижением минеральной плотности костного матрикса. Сильно осложняет диагностическую задачу наличие латентных или недавно проявившихся заболеваний, сопровождающихся процессами костной дисплазии [13][14][15].…”

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Differential Diagnosis of a Solitary Bone Lesion Using SPECT/CT Method

Рыжков

Крылов²,

Каспшик³

et al. 2021

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Relevance: Radionuclide bone scan signs of lesions are not specific and require radiological identification. Hybrid tomographic technology is a combination of spatial distribution of radiopharmaceuticals and its anatomical binding. Thus, makes it possible to accurately identify the affected bone structure and also determine the nature of this changes (radiological anatomy). In cancer patients, SPECT/CT method allows to visualize tumor pathology in the bones, but also keeps to a minimum errors and other excessive examinations.Purpose: To demonstrate the most frequent diseases and conditions that simulate tumor lesions in bones on bone scan.Material and methods: We analyzed the results of examinations of 81 patients with various tumor diseases (2015–2020). Bone scan was performed in the whole body 3 hours later, after intravenous administration of 99mTc-phosphotech on a Symbia E, T2 (Siemens, Germany). SPECT/CT was performed after WB Bone Scan.Results: The most frequent reasons for the focal increased uptake of radiopharmaceutical were: reactive increase in metabolism and as a result additional mineral repair: deforming osteoarthritis, osteophytes; post‑traumatic and postoperative changes; fractures (osteoporosis and stress fractures); inflammatory processes; focal uptake due to the benign neoplasms of bones and dysplasia. Combination of highly sensitive but non-specific scintigraphy with highly specific computed tomography makes it especially useful in anatomically difficult areas.Conclusion: SPECT/CT reveals a direct pater of anatomical and structural abnormalities with changes in bone tissue metabolism in case of different injuries and minimizes a number of ambiguous conclusions. SPECT/CT in oncological practice greatly helps nuclear medicine physician in the differential diagnostic process and reduces time of examination for the patient.

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Secondary Hypertrophic Osteoarthropathy (Pierre Marie–bamberger Syndrome)

Cited by 2 publications

References 0 publications

Science research experience in the use of radiopharmaceuticals at the N.N. Petrov NMRC of Oncology

Science research experience in the use of radiopharmaceuticals at the N.N. Petrov NMRC of Oncology

Differential Diagnosis of a Solitary Bone Lesion Using SPECT/CT Method

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