Secondary Bilateral Angle Closure Glaucoma due to Topiramate

Paciuc-Beja, Miguel; Retchkiman-Bret, Myriam; Velasco‐Barona, Cecilio; Galicia-Alfaro, Victor Hugo

doi:10.1155/2011/594051

Cited by 2 publications

(1 citation statement)

References 12 publications

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Section: Resultsunclassified

Topiramate-induced acute angle closure: A systematic review of case reports and case series

Owaifeer

AlSultan

Badawi

2022

Indian J Ophthalmol

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Topiramate-induced acute angle closure (TiAAC) is a potentially vision-threatening side effect of topiramate (TPM) use. The purpose of this article is to review demographic characteristics, clinical features, and management options of TiAAC. A systematic literature search of all reported cases and case series of TiAAC was conducted in the following search engines: PubMed, Web of Science, Google Scholar, Elsevier, and EBSCO. Seventy-three publications describing 77 cases were included. 58 (75.3%) patients were female, and the mean age was 34.88 ± 11.21 years (range, 7–57). The most commonly reported indication of TPM use was migraine headache (59.7%), and the mean duration from starting treatment until the onset of angle closure was 14.1 ± 31.5 days. All cases were managed by immediate cessation of TPM and topical therapy. In addition, systemic medications (carbonic anhydrase inhibitors, hyperosmotic agents, and steroids) were used in 51 patients (66.2%). A laser and/or surgical intervention was performed in 10 patients (13%). After commencement of treatment, the mean duration until the resolution of TiAAC was 3.9 ± 3.6 days (range, 1–18). The findings of our study present a summary of the current body of evidence provided by case reports and case series on TiAAC. In conclusion, the onset of angle closure following TPM use peaks at 2 weeks after initiating treatment, and in most cases, successful management can be achieved by discontinuing TPM and initiating appropriate medical therapy.

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Section: Resultsunclassified

Topiramate-induced acute angle closure: A systematic review of case reports and case series

Owaifeer

AlSultan

Badawi

2022

Indian J Ophthalmol

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Simultaneous Bilateral Acute Angle-Closure Glaucoma in Miller Fisher Syndrome

Štěpánková

Kinstova

Gažová

et al. 2019

CSO

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Purpose: To report a case of patient with Miller Fisher syndrome, complicated by simultaneous bilateral acute angle-closure glaucoma in her slightly (+1.5) hyperopic eyes. Methods: We present a case report of a 71-year-old female patient presenting with total ophthalmoplegia, areflexia, ataxia and bilateral acute angle-closure glaucoma. Results: The initial ocular examination revealed hand motion in the both eyes and oedematic corneas. Initial intraocular pressure was immeasurable high (measurment by Tonopen Avia). Measurement was possible after intravenous Mannitol 20 % infusion on both eyes as 54 and 56 mm Hg, respectively. Local medical therapy of pilocarpine, timolol, dorsolamide and dexamethasone improve intraocular pressure into normal limits within several hours. Prophylactic peripheral Nd-YAG laser iridotomy was performed on a both eyes two days later. Systemic treatment involved plasma exchange and rehabilitation program. Subsequent cataract surgery on both eyes with posterior capsule lens implantation improve the best corrected visual acuity on right eye from 0.5 to 1.0 and the left eye from 0.5 to 0.8, respectively. Intraocular pressure is within normal limits without any glaucoma therapy. Follow up period is three years. Conclusions: This is the second reported case of patient with Miller Fisher syndrome and simultaneous bilateral acute angle-closure glaucoma and the fifth reported case of Miller Fisher syndrome and acute angle-closure glaucoma. Treatment for both conditions made a very good recovery.

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Secondary Bilateral Angle Closure Glaucoma due to Topiramate

Cited by 2 publications

References 12 publications

Topiramate-induced acute angle closure: A systematic review of case reports and case series

Topiramate-induced acute angle closure: A systematic review of case reports and case series

Simultaneous Bilateral Acute Angle-Closure Glaucoma in Miller Fisher Syndrome

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