Second-Trimester Abortion After Vaginal Termination of Pregnancy

Wright, CharlesS.W.; Campbell, Stuart; Beazley, J. M.

doi:10.1016/s0140-6736(72)90995-6

Cited by 130 publications

(31 citation statements)

References 5 publications

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“…The clinical signifi cance of a tear in the cervical tissue is, however, unknown. There are studies showing an increased risk of secondtrimester spontaneous abortion [12][13][14] and preterm de livery [ 15] in women with a previous, induced abortion in the first trimester. Other studies on this issue do not con firm this [16][17][18][19][20], Most studies, however, do not analyze the material with regard to the degree of dilatation, mak ing conclusions difficult regarding the dangers of dilata tion to more than 9 mm.…”

Section: Discussionmentioning

confidence: 99%

Risk of Damage to the Cervix by Dilatation for First-Trimester-Induced Abortion by Suction Aspiration

Molin¹

1993

Gynecol Obstet Invest

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A fall in cervical resistance to dilatation for first-trimester-induced abortions has been observed in previous studies and considered a sign of tearing of the cervical tissue. In a study of 104 patients undergoing first-trimester abortion a fall in resistance was found in 12.5 % of women in whom the cervix was dilated to 9 mm, and in 66.7% when dilatation reached 11 mm. No difference between parous and nulliparous women was found.

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Section: Discussionmentioning

confidence: 99%

Risk of Damage to the Cervix by Dilatation for First-Trimester-Induced Abortion by Suction Aspiration

Molin¹

1993

Gynecol Obstet Invest

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“…The complications of surgical termination are infection, cervical laceration, incomplete evacuation, uterine perforation, hemorrhage, and anesthesia complications [1,2].…”

Section: Introductionmentioning

confidence: 99%

Effect of isosorbide mononitrate for cervical ripening before surgical termination of pregnancy in the first trimester

Phusaanantakul

Promsonthi

Chanrachakul

2010

Intl J Gynecology & Obste

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“…Surgical termination of pregnancy is associated with complications such as uterine perforation, cervical laceration and incomplete evacuation of the uterus 1,2 . Cervical ripening prior to surgical termination of pregnancy has been shown to reduce the associated operative morbidity 3±5 .…”

Section: Introductionmentioning

confidence: 99%

A comparison of isosorbide mononitrate, misoprostol and combination therapy for first trimester pre‐operative cervical ripening: a randomised controlled trial

Ledingham

Thomson

Lunan

et al. 2001

BJOG

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Objective To determine whether a combined therapy with isosorbide mononitrate (40mg) and misoprostol (400mg) for pre-operative cervical ripening in the ®rst trimester would result in improved clinical effectiveness, and fewer side effects compared with each agent used alone.Design Randomised controlled trial. Setting Glasgow Royal In®rmary.Population Sixty-six primigravid women scheduled for suction termination of pregnancy.Methods Women were randomly assigned to receive before surgery, per vaginam, isosorbide mononitrate 40 mg (n 22), misoprostol 400 mg (n 22) or both agents together [isosorbide mononitrate 40 mg and misoprostol 400 mg] (n 22).Main outcome measures 1. To assess the cumulative force required to dilate the cervix to 8 mm; 2. the onset of new symptoms before termination of pregnancy. Conclusions We have not shown any advantage of combining misoprostol with the nitric oxide donor isosorbide mononitrate compared with misoprostol alone for pre-operative cervical ripening in the ®rst trimester.

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Second-Trimester Abortion After Vaginal Termination of Pregnancy

Cited by 130 publications

References 5 publications

Risk of Damage to the Cervix by Dilatation for First-Trimester-Induced Abortion by Suction Aspiration

Risk of Damage to the Cervix by Dilatation for First-Trimester-Induced Abortion by Suction Aspiration

Effect of isosorbide mononitrate for cervical ripening before surgical termination of pregnancy in the first trimester

A comparison of isosorbide mononitrate, misoprostol and combination therapy for first trimester pre‐operative cervical ripening: a randomised controlled trial

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