“…If a second primary lung cancer develops, subsequent resection may be offered to selected patients. 8,9 Although in most cases sleeve lobectomy may involve resection of one lobe or of the right middle and lower lobes, we have tried various complex atypical resections for patients with noncompromised lung function and larger centrally located tumors to avoid pneumonectomy. This study summarizes our experi-T he risk of perioperative mortality and morbidity is greater for pneumonectomy than for smaller pulmonary resections.…”
We suggest that this extended sleeve lobectomy, which is technically demanding, should be considered in patients with centrally located lung cancer, because this lung-saving operation is safer than pneumonectomy and is equally curative.
“…If a second primary lung cancer develops, subsequent resection may be offered to selected patients. 8,9 Although in most cases sleeve lobectomy may involve resection of one lobe or of the right middle and lower lobes, we have tried various complex atypical resections for patients with noncompromised lung function and larger centrally located tumors to avoid pneumonectomy. This study summarizes our experi-T he risk of perioperative mortality and morbidity is greater for pneumonectomy than for smaller pulmonary resections.…”
We suggest that this extended sleeve lobectomy, which is technically demanding, should be considered in patients with centrally located lung cancer, because this lung-saving operation is safer than pneumonectomy and is equally curative.
“…Consistent with these findings has been the observation that central lung cancers that have been treated with sleeve resection also may have a high rate of metachronous tumors. Van Schil et al 47 found that metachronous tumors developed in 11 of 145 patients undergoing sleeve resection.…”
Section: Recurrence Of the Original Lung Cancer And Development Of Nementioning
The strong and prolonged inhibition of gastric acid production induced by omeprazole seems to be effective in preventing chemotherapy-induced gastroduodenal mucosal injury. Further trials are necessary to verify whether such a prevention of endoscopically observed injury can translate into prevention of clinically significant injury.
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