We analyse a tension between the D0 and CDF inclusive jet data and the perturbative QCD calculations, which are based on the ABKM09 and ABM11 parton distribution functions (PDFs) within the nuisance parameter framework. Particular attention is paid on the uncertainties in the nuisance parameters due to the data fluctuations and the PDF errors. We show that with account of these uncertainties the nuisance parameters corresponding to the luminosity uncertainties in the D0 and the CDF data sets take the values r D0 norm = 4.1 ± 1.3 and r CDF norm = 5.4 ± 1.7, respectively, while dropping luminosity uncertainty leads to variation of the PDFs well within uncertainties. A statistical bias of the estimator based on the nuisance parameters is also discussed.