Second-generation ventricular assist devices

Graefe, Roland; Groß-Hardt, Sascha

doi:10.1016/b978-0-12-810491-0.00004-7

Cited by 2 publications

(10 citation statements)

References 37 publications

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“…Since first-generation pumps were limited by their large size, high noise emissions, decreased patient mobility, and durability issues, research to develop smaller, more reliable devices was initiated [15]. Some of the features that characterize the second-generation LVADs from the first are that they are continuous, rather than pulsatile pumps, and that they produce axial blood motion using a rotor [34]. The second-and third-generation VADs replace or support only the ventricular function.…”

Section: Second Generationmentioning

confidence: 99%

“…The second-and third-generation VADs replace or support only the ventricular function. There is no direct attempt made to imitate the modality of the native, ventricular function [20,34].…”

Section: Second Generationmentioning

confidence: 99%

“…It has been used since the mid-1980s. Is a centrifugal pump that provides extracorporeal left and/or right ventricular assistance for short-term bridge-to-bridge, bridge-to-recovery, and bridge-to-transplant support [34,35].…”

Section: Second Generationmentioning

confidence: 99%

“…A few years later in Europe, in 1999, the ROTAFLOW (Maquet, Hirrlingen, Germany) was approved for pulmonary and/or ventricular support, including cardiopulmonary bypass, or used in the framework of extracorporeal membrane oxygenation (ECMO) procedures [34].…”

Section: Second Generationmentioning

confidence: 99%

“…This action provides forward flow in the pulmonary circulation and unloading of the RV [39]. The Impella 2.5, CP, 5.0, 5.5, and LD have also been designed and approved for use in High-Risk Percutaneous Coronary Interventions (HRPCI) and cardiogenic shock [34].…”

Section: Second Generationmentioning

confidence: 99%

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A Historical Review of Mechanical Circulatory Support

Martinez¹,

Alberson²,

Guerra³

et al. 2023

Ventricular Assist Devices - Advances and Applications in Heart Failure

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Meaningful and contemporary data regarding the clinical use of mechanical circulatory support (MCS) is founded on the work conducted in the 1950s when a “heart-lung” machine was incorporated to provide support during surgical interventions. Following this milestone, the need to support artificial circulation in patients with heart failure initiated an investigational and legislative collaboration to implement the mission-oriented Artificial Heart Program in the United States during the 1960s. In the subsequent decades, technological discoveries have integrated a series of mechanical systems employed as therapeutic options for short- and long-term artificial circulation in children and adults with advanced heart failure. Since their clinical application, MCS devices have been employed as a bridge to transplantation in over 4000 patients globally. In recent years, the adverse effects and economic burden of MCS have been counterbalanced by the harmonization of therapeutic protocols, the inclusion of multidisciplinary insight, and the allowance of families and patients to participate in shared decision making to address candidacy. In this chapter, we provide a review of the historical aspects of MCS, a therapeutic option for overcoming complexities encountered in reestablishing adequate hemodynamic states and providing a reasonable quality of life.

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Section: Second Generationmentioning

confidence: 99%

“…The second-and third-generation VADs replace or support only the ventricular function. There is no direct attempt made to imitate the modality of the native, ventricular function [20,34].…”

Section: Second Generationmentioning

confidence: 99%

Section: Second Generationmentioning

confidence: 99%

Section: Second Generationmentioning

confidence: 99%

Section: Second Generationmentioning

confidence: 99%

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