Second generation stationary digital breast tomosynthesis system with faster scan time and wider angular span

Calliste, Jabari; Wu, Gongting; Laganis, P; Spronk, Derrek; Jafari, Houman; Olson, Kyle; Gao, Bo; Lee, Yueh Z.; Zhou, Otto; Lu, Jianping

doi:10.1002/mp.12393

Cited by 15 publications

(20 citation statements)

References 37 publications

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“…Reduces tissue overlap and enhances image contrast for the visualization of malignant calcifications Improves the detection of masses and distortions associated with calcifications Better depicts the trajectory of vascular calcifications and associated tubular vessels Facilitates the diagnosis of skin calcifications Cons Some malignant calcifications may be suppressed at DBT and SM Lower in-plane resolution Artifacts may jeopardize the depiction of calcifications Increased radiation dose with some protocols in-plane and depth resolution, which may create shorter imaging times and fewer artifacts, is being developed and will soon be on the market with the potential to improve lesion conspicuity and cancer detection (63).…”

Section: Prosmentioning

confidence: 99%

Calcifications at Digital Breast Tomosynthesis: Imaging Features and Biopsy Techniques

et al. 2019

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Full-field digital mammography (FFDM), the standard of care for breast cancer screening, has some limitations. With the advent of digital breast tomosynthesis (DBT), improvements including decreased recall rates and increased cancer detection rates have been observed. The quasi-three-dimensional capability of DBT reduces breast tissue overlap, a significant limitation of FFDM. However, early studies demonstrate that a few cancers detected at FFDM may not be diagnosed at DBT-only screening, and lesions with calcifications as the dominant feature may look less suspicious at DBT or not be visible at all. These findings support the use of combined FFDM and DBT protocols to optimize screening performance. However, this combination would approximately double the patient's radiation exposure. The development of computer algorithms that generate two-dimensional synthesized mammography (SM) views from DBT has improved calcification conspicuity and sensitivity. Therefore, SM may substitute for FFDM in screening protocols, reducing radiation exposure. DBT plus SM demonstrates significantly better performance than that of FFDM alone, although there are reports of missed malignant calcifications. Thus, some centers continue to perform FFDM with DBT. Use of DBT in breast imaging has also necessitated the development of DBT-guided biopsy. DBT-guided biopsy may have a higher success rate than that of stereotactic biopsy, with a shorter procedure time. While DBT brings substantial improvements to breast cancer imaging, it is important to be aware of its strengths and limitations regarding detection of calcifications. This article reviews the imaging appearance of breast calcifications at DBT, discusses calcification biopsy techniques, and provides an overview of the current literature.

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Section: Prosmentioning

confidence: 99%

Calcifications at Digital Breast Tomosynthesis: Imaging Features and Biopsy Techniques

et al. 2019

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“…The sDBT system 16 consisted of a CNT-enabled linear x-ray source array (XinRay Systems, Inc.) that was retrofitted to a Hologic Selenia Dimensions DBT unit and positioned to collect a standard CC view [ Fig. 1(a)].…”

Section: Acquiring the Imagesmentioning

confidence: 99%

“…The average nominal anode focal spot size was 1.1 mm, and, as operated in these experiments, the system resolution corresponding to the frequency at 10% of the normalized MTF was 5.4 cycles∕mm. 16 The breast compression equipment and digital detector remained original to the Hologic Selenia Dimensions system, which was operated without an antiscatter grid. The a-Se direct conversion detector had a field-of-view 29 × 24 cm and was operated in a 2 × 2 binned mode with an effective detector pixel size of 140 × 140 μm, which also defines the size of the projection image pixel.…”

Section: Acquiring the Imagesmentioning

confidence: 99%

“…sDBT offers a higher spatial and temporal resolution than the rotating-source DBT devices currently in clinical use. 15,16 The improved performance is made possible by a unique x-ray tube design, which consists of a distributed and fixed array of carbon nanotube (CNT)-enabled x-ray sources. 17 CNT cathodes release the electrons needed for x-ray generation at room temperature and essentially instantaneously.…”

Section: Introductionmentioning

confidence: 99%

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Phantom-based study exploring the effects of different scatter correction approaches on the reconstructed images generated by contrast-enhanced stationary digital breast tomosynthesis

et al. 2018

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Stationary digital breast tomosynthesis (sDBT) is an emerging technology in which the single rotating x-ray tube is replaced by a fixed array of multiple carbon nanotube-enabled sources, providing a higher spatial and temporal resolution. As such, sDBT offers a promising platform for contrast-enhanced (CE) imaging. However, given the minimal enhancement above background with standard operational tube settings and iodine dosing, CE breast imaging requires additional acquisition steps to isolate the iodine signal, using either temporal or dual energy subtraction (TS or DES) protocols. Also, correcting for factors that limit contrast is critical, and scatter and noise pose unique challenges during tomosynthesis. This phantom-based study of CE sDBT compared different postacquisition scatter correction approaches on the quality of the reconstructed image slices. Beam-pass collimation was used to sample scatter indirectly, from which an interpolated scatter map was obtained for each projection image. Scatter-corrected projections provided the information for reconstruction. Comparison between the application of different scatter maps demonstrated the significant effect that processing has on the contrast-to-noise ratio and feature detectability ([Formula: see text]) in the final displayed images and emphasized the critical importance of scatter correction during DES.

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“…Different types of markers are used commonly in the construction of calibration phantoms. Tungsten [12], steel [14] or ruby [15] spheres are common and so are hole plates [16]. A detailed analysis of the influence of different sources of errors on the accuracy of this approach to geometric calibration can be found in [17] and [18].…”

Section: A Contributionmentioning

confidence: 99%

Calibration of Robotic Manipulator Systems for Cone-Beam Tomography Imaging

Blumensath

O'Brien

Wood

2018

IEEE Trans. Nucl. Sci.

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Abstract-Iterative reconstruction of tomographic data relies on the precise knowledge of the geometric properties of the scan system. Common tomography systems such as rotational tomography, C-arm systems, helical scanners or tomosynthesis scanners generally use motions described by few rotational or linear motion axis. We are interested in applications in nondestructive testing, where objects might have large aspect rations and complex shapes. For these problems, more complex scan trajectories are required which can be achieved with robotic manipulator systems that have several linear or rotational degrees of freedom.For the geometric calibration of our system, instead of using an approach that scans a calibrated phantom with markers at known relative position, we propose an approach that uses one (or several) markers with unknown relative positions. The fiducial marker is then moved by a known amount along one degree of freedom, thus tracing out a "virtual" phantom. Using the assumed spacial locations of the markers together with the locations of the markers on the imaging plane, we use a nonlinear optimisation method to estimate the orientation of the linear and rotational manipulator axis, the detector and source location and the detector orientation.

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Second generation stationary digital breast tomosynthesis system with faster scan time and wider angular span

Cited by 15 publications

References 37 publications

Calcifications at Digital Breast Tomosynthesis: Imaging Features and Biopsy Techniques

Calcifications at Digital Breast Tomosynthesis: Imaging Features and Biopsy Techniques

Phantom-based study exploring the effects of different scatter correction approaches on the reconstructed images generated by contrast-enhanced stationary digital breast tomosynthesis

Calibration of Robotic Manipulator Systems for Cone-Beam Tomography Imaging

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