Second European Stroke Science Workshop

Mattle, Heinrich; Brainin, Michael; Chamorro, Ángel; Dichgans, Martin; Lees, Kennedy R.; Leys, Didier; Michel, Patrik

doi:10.1161/strokeaha.114.005583

Stroke

2014

DOI: 10.1161/strokeaha.114.005583

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Second European Stroke Science Workshop

Heinrich Mattle

Michael Brainin

Ángel Chamorro

et al.

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Cited by 2 publications

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“…During recent years, the ESO has been actively engaged in new important challenges like the ESO Conference and the new standardized guidelines policy. The launch of the first ESO Conference in April 2015 (9), the publication of the ESO guidelines for the management of spontaneous ICH in the present issue of the International Journal of Stroke , and multiple other educational and scientific activities (11,–14) emphasize the strong determination of the ESO to further promote stroke management, education, and research in Europe.…”

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confidence: 99%

The European Stroke Organisation (ESO) Guidelines

Steiner

Salman

Ntaios

2014

International Journal of Stroke

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In 2008, the European Stroke Organisation (ESO) updated the European Stroke Initiative (EUSI) recommendations for the management of ischemic stroke and transient ischemic attack, initially published in 2000 and updated in 2003 (1-3). Since then, the ESO has begun the process of implementing a new standardized system for the production and presentation of evidencebased clinical guidelines. The ESO guidelines committee agreed on two major developments: use of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system (4-7); and the transition to a model in which several guideline documents deal with specific topics of interest called modules rather than a single document on a large topic.The GRADE system has a series of advantages over other systems that include clear separation between quality of evidence and strength of recommendation, explicit comprehensive criteria for downgrading and upgrading quality of evidence ratings, transparent process of moving from evidence to recommendations, explicit evaluation of the importance of outcomes of alternative management strategies, explicit acknowledgment of values and preferences, and clear pragmatic interpretation of strong versus weak recommendations for clinicians, patients, and policy makers (4-7). In summary, the GRADE approach starts with the formulation of the PICO (population, intervention, comparator, and outcome) questions. The selected outcomes are rated using a 9-degree scale (7-9: critical; 4-6: important; 1-3: of limited importance) and a search strategy is formulated. After a thorough literature search leading to the identification of all available evidence, eligible studies are then selected and their data are extracted and analyzed. The results can be imported into the GRADEPro software (8), allowing for efficient quality grading of the available evidence for each outcome and each clinical question. Then we determine the direction (either 'against' or 'for') and strength of the recommendation (either 'strong' or 'weak'), and finally the recommendation is formulated using a standardized language (4-7).The second major development in the ESO guidelines policy was to move from the classical model of a single guideline document on a major topic -e.g. management of ischemic stroke, transient ischemic attack, and hemorrhagic stroke -to subdivision of the major topic into focused modules. This enables the ESO Guidelines Committee to react quickly when new developments in a specific area of stroke medicine occur, and update recommendations on the related module with speed. With the

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confidence: 99%

The European Stroke Organisation (ESO) Guidelines

Steiner

Salman

Ntaios

2014

International Journal of Stroke

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Review and prioritization of stroke research recommendations to address the mission of the World Stroke Organization: a call to action from the WSO Research Committee

Sacco

Sandercock

Endres

et al. 2015

International Journal of Stroke

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Second European Stroke Science Workshop

Cited by 2 publications

References 66 publications

The European Stroke Organisation (ESO) Guidelines

The European Stroke Organisation (ESO) Guidelines

Review and prioritization of stroke research recommendations to address the mission of the World Stroke Organization: a call to action from the WSO Research Committee

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