“…Tamara Abou-Antoun 1 , Rachelle Mikhael 1& , Marcel Massoud 2& , Georges Chahine 2 , Aline Saad 3 * most serious long-term toxicities documented in survivors of HL include secondary malignant neoplasms (SMNs), cardiovascular diseases, hypothyroidism, and fertility issues (Lorigan et al, 2005;NCCN, 2015). Among SMNs, solid tumors were more commonly seen compared to hematologic malignancies (Aleman et al, 2012;NCCN, 2015). In fact, RT used as a component of first-line therapy in HL increased the risk of developing secondary solid tumors particularly affecting the lungs, breast, connective tissues and gastrointestinal tract (Constine et al, 2008;Oeffinger et al, 2013;Choi et al, 2014;NCCN, 2015).…”