Seborrhoeic keratosis or occult malignant neoplasm of the skin?

Abstract

Although the association of seborrhoeic keratosis and skin malignancy appears to be relatively uncommon, the possibility of such an association cannot be ruled out.

Seborrhoeic keratosis and malignancy: Collision tumour or malignant transformation?

“…The study also found that seborrhoeic keratoses associated with BCC were more likely to have clinical features or history of inflammation, bleeding, crusting, erosion or ulceration than ‘benign’ seborrhoeic keratoses 2 . These are features that are likely to represent malignant change in seborrhoeic keratoses, as noted in other studies 2–5 …”

Dark Brownish Cutaneous Mass in the Cavum Concha

“…4,5 Clinically, SK appears as sharply demarcated, tan to brownish in color and has a slightly raised, verrucous surface with soft and friable consistency, often showing as keratotic plugs stacked on the skin. 2 However, it is not easy to differentiate SK from both premalignant and malignant lesions by close visual inspection only, 2 even though clinical diagnosis can be aided with noninvasive techniques, such as dermoscopy and confocal laser surface microscopy.…”

Seborrheic keratosis with basal clear cells: A distinctive microscopic mimic of melanoma in situ

“…Although the distinctive clinical morphology of seborrheic keratoses generally allows dermatologists to readily make this distinction, there still appear to be a subset of melanomas that clinically resemble seborrheic keratoses. 1,2 For this reason, biopsies of seborrheic keratoses are frequently performed.…”