Seborrheic keratosis of the cheek simulating squamous cell carcinoma

Abstract

Introduction Seborrheic keratoses are benign tumours that occur electively on the head, neck and trunk. It can be confused on its clinical appearance with other skin tumours and it is the histological examination that establishes the diagnosis. We report a case of seborrheic keratosis simulating squamous cell carcinoma. Observation A 62-year-old woman consulted for a budding right jugal lesion that had been evolving for 6 months. Clinical examination found a right jugal budding lesion with crusts on its surface, pedunculated, surrounded by a hyperpigmented halo at its base, firm to palpation, painless and non bleeding on contact. An initial biopsy of the lesion for histological examination confirmed the diagnosis, followed by complete surgical excision. Discussion Seborrheic keratoses are benign tumours that occur mainly in subjects over 50 years of age. They occur electively on the trunk, head and neck. Its clinical aspect is generally typical but sometimes misleading, as found in our case; only histology allows to make the diagnosis of certainty.

Perioral Clonal Variant of Seborrheic Keratosis: Diagnostic Challenges

“…Clinical features like ulceration and erythema around SK lesions have a possible role in tumour formation. Criteria for diagnosis of tumour in SK are cytologic atypia, mitosis with similar features of SK, hyperkeratosis, parakeratosis, papillomatosis and pseudo horn cyst [ 18 , 19 ].…”

“…Other histological features include acantholysis, dyskeratosis, spongiosis, squamous eddies, necrosis and basal cell vacuolization. Clinicians and pathologists should always be aware of the possibility of squamous cell carcinoma or basal cell carcinoma arising in SK and should have an increased suspicion for it [ 19 ].…”

Classification of Skin Lesion Images Using Artificial Intelligence Methodologies through Radial Fourier–Mellin and Hilbert Transform Signatures

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