Sebaceous Lymphadenoma: Radiology–Pathology Correlation

Dababneh, Melad; Griffith, Christopher C.; Patel, Mihir R.; Magliocca, Kelly R.

doi:10.1007/s12105-020-01266-5

Cited by 2 publications

(1 citation statement)

References 18 publications

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“…No case series of SA cytopathology could be found in our review of the English‐language literature. Nonetheless, a single multi‐institutional case series (nine cases) 4 and a number of single and dual case reports of SLA have been reported 5–29 . We present the FNA biopsy findings from two examples of benign sebaceous neoplasia—one SA and one SLA—and discuss the cytomorphological features and diagnostic challenges associated with each.…”

Section: Introductionmentioning

confidence: 96%

Cytopathology of benign sebaceous salivary gland neoplasia: Comparison of two analogous yet dissimilar entities

Sheldon

Wakely

2023

Cytopathology

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IntroductionBenign sebaceous salivary gland (SG) neoplasms represent approximately 0.2% of all salivary gland neoplasms. Not only are fine needle aspiration (FNA) biopsy findings of sebaceous adenoma (SA) and sebaceous lymphadenoma (SLA) limited, but their findings are also rarely compared with one another.Materials and MethodsOur cytopathology files were searched for examples of benign sebaceous SG neoplasms with concomitant histopathological verification. FNA biopsy and cell collection were performed using standard technique.ResultsOne case each of parotid SA and parotid SLA showed markedly dissimilar cytomorphology. The SA case was composed of a repetitive population of profusely multivacuolated polygonal cells with single and multiple nuclei, and was specifically recognised cytologically as a sebaceous neoplasm due to its characteristic cytoplasmic vacuolisation. The SLA case, however, was characterised by smears filled primarily with lymphocytes and only scant widely scattered basaloid cell clusters. A non‐specific diagnosis of basaloid neoplasm was rendered. In retrospect, recognition of sebaceous differentiation was limited to rare cell groups.ConclusionThough nominally, epidemiologically, and to a degree histopathologically analogous, the cytopathology of SA and SLA are markedly dissimilar, reflecting the dominant cell component in each. With FNA biopsy, a specific interpretation is more likely for SA than SLA due to the overwhelming obscuring lymphoid population in the latter.

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Section: Introductionmentioning

confidence: 96%

Cytopathology of benign sebaceous salivary gland neoplasia: Comparison of two analogous yet dissimilar entities

Sheldon

Wakely

2023

Cytopathology

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Multiple Parotid Sebaceous Lymphadenoma: A Case Report and Review of the Literature

Yang,

Tang,

Wang

et al. 2023

CMIR

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Introduction/Background: Sebaceous lymphadenoma is a rare parotid gland neoplasm. Up to now, there have been several studies that have discussed the imaging manifestations of salivary sebaceous lymphadenoma. In this paper, we have reported a case of multiple parotid sebaceous lymphadenoma demonstrated by ultrasound, CT scan, and MRI examinations, including diffusion-weighted imaging. To the best of our knowledge, this report is the first one on DWI findings of sebaceous lymphadenomas, and also the first report on multiple lesions in unilateral parotid gland. Case Presentation: A 41-year-old woman presented with a nodule in the left parotid region. The lesion has grown slowly for 2 months and was not associated with any discomfort. Ultrasound, CT scan, and MRI examinations, including diffusion-weighted imaging, showed multiple nodules in the left parotid gland of a 41-year-old woman. These nodules were heterogeneous on CT scan and MRI examinations, and intratumorally multifocal fat and cystic areas were detected. On ultrasound examination images, these lesions were heterogeneous hypoechoic echotexture with multifocal irregular hyperechogenic areas, without significant blood flow. The patient underwent a left parotidectomy. Histopathologic sections showed nests of sebocytes distributed in lymphoid follicles and lymphocyte background, with obvious cystic changes. The patient recovered after receiving left parotidectomy. The microscopy diagnosis was parotid sebaceous lymphadenoma. Conclusion: This case highlights the main imaging feature of parotid sebaceous lymphadenomas, namely an intraparotid heterogeneous nodule containing multifocal fat and cystic areas, and its possible origination from an intraparotid lymph node. This case also indicates that this rare lesion may occur at multiple sites.

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Sebaceous Lymphadenoma: Radiology–Pathology Correlation

Cited by 2 publications

References 18 publications

Cytopathology of benign sebaceous salivary gland neoplasia: Comparison of two analogous yet dissimilar entities

Cytopathology of benign sebaceous salivary gland neoplasia: Comparison of two analogous yet dissimilar entities

Multiple Parotid Sebaceous Lymphadenoma: A Case Report and Review of the Literature

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