Sebaceous gland carcinoma of right lower eyelid: A case report

Abstract

A 50 year old lady presented to eye opd with a painless, nodular lid mass in right lower eye lid for 6 months with an aggressive growth for last 3 months. Physical examination revealed a solid mass of size about 30 mm x 30 mm x 20 mm. A complete excision of the mass with a 3mm clear margin was done along with lid reconstruction using Tanzel Flap technique. Biopsy and immunohistochemistry study revealed sebaceous cell carcinoma of right lower eye lid.

Direct Closure Technique for Superior Palpebra Defect in Sebaceous Gland Carcinoma Palpebra

“…Suspicion of sebaceous gland carcinoma should be considered for eyelid lesions that do not respond adequately to the given management, as experienced by the patient who had been seeking treatment for the past year and had even tried herbal remedies. [7][8][9] The patient also has age-related risk factors, being over 50 years old, and is female, which aligns with the literature reference previously reported, where this condition is more commonly found in women and individuals over 50 years old. SGC predominantly affects the upper eyelid in 2/3 of cases, 20% in the lower eyelid, and 4-7% in the caruncle.…”

“…The higher presence of meibomian and Zeis glands in the upper eyelid plays a significant role in why this tumor is more frequently found in that area. [6][7][8] In Sebaceous gland carcinoma is more frequently found on the skin of the eyelids compared to other parts of the body. 6,8,9 The most common location on the eyelid is in the Meibomian glands, but it can also occur in the Zeis glands, sebaceous glands of the caruncle, and pilosebaceous glands of the eyelids and eyebrows.…”