Sebaceous carcinoma of right upper eyelid: case report and literature review

Abstract

Sebaceous gland carcinoma is a rare fast growing cutaneous cancer. It is derived from the adenxal epithelium of sebaceous glands. Sebaceous carcinomas are generally divided into those occurring in periocular or extraocular locations. Ocular sebaceous carcinomas occur most commonly in upper eye lid, in the elderly with a predilection for females and Asian populations. Due to its clinical resemblance with chalazion or other chronic inflammatory conditions, there is a delay in diagnosis. Due to its rarity, we present a case of sebaceous carcinoma of right upper eyelid in a 65-year-old female.

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“…The reported incidence is less than 1% of all skin malignancies. 1 It accounts for 1-5.5% of all eyelid malignancies with more predilections for upper eyelid. 2 It may originate from the meibomian glands in the tarsus, zeis glands at the eyelid margin or sebaceous glands at caruncle or eyebrows.…”