Sebaceous Adenoma

Biological Behavior of the Sebaceous Carcinoma of the Head

“…The nomenclature and the criteria for the classification of sebaceous tumors are still subjects of discussion 6–9 …”

“…5 The nomenclature and the criteria for the classification of sebaceous tumors are still subjects of discussion. [6][7][8][9] SC histologically consists of well-circumscribed lobules of neoplastic cells, with eosinophil cytoplasm and severe atypia, some of which have foamy or glassy lobules; cytologic atypia, including nuclear pleomorphism and frequent mitosis, is always present (Figure 1). 10 The average age of onset is approximately 70 years old.…”

Sebaceous carcinoma in situ as a concept and diagnostic entity.

“…Well- and moderately-differentiated nodular/cystic SCIS was called sebaceous adenoma initially by early authors [ 3 , 28 ] and subsequently has been called this way by many up to this day. However, in an article published in 1998, Nussen and Ackerman revised this concept and stated that the so-called sebaceous adenoma is not a benign neoplasm but sebaceous carcinoma [ 29 ].…”