“…Well-documented bioactive metabolites of marine algae [21] include brominated phenols [20], brominated oxygen heterocyclics, nitrogen heterocyclics, kainic acids, guanidine derivatives, phenazine derivatives, amino acids and amines, sterols [22], sulfated polysaccharides [4,23,24], and prostaglandins [25]. Fucoxanthin, a type of xanthophyll and an accessory pigment in the chloroplasts of algae, has also shown various beneficial effects [26].…”
Section: Bioactive Components Of Marine Algaementioning
For their various bioactivities, biomaterials derived from marine algae are important ingredients in many products, such as cosmetics and drugs for treating cancer and other diseases. This mini-review comprehensively compares the bioactivities and biological functions of biomaterials from red, green, brown, and blue-green algae. The anti-oxidative effects and bioactivities of several different crude extracts of algae have been evaluated both in vitro and in vivo. Natural products derived from marine algae protect cells by modulating the effects of oxidative stress. Because oxidative stress plays important roles in inflammatory reactions and in carcinogenesis, marine algal natural products have potential for use in anti-cancer and anti-inflammatory drugs.
“…Well-documented bioactive metabolites of marine algae [21] include brominated phenols [20], brominated oxygen heterocyclics, nitrogen heterocyclics, kainic acids, guanidine derivatives, phenazine derivatives, amino acids and amines, sterols [22], sulfated polysaccharides [4,23,24], and prostaglandins [25]. Fucoxanthin, a type of xanthophyll and an accessory pigment in the chloroplasts of algae, has also shown various beneficial effects [26].…”
Section: Bioactive Components Of Marine Algaementioning
For their various bioactivities, biomaterials derived from marine algae are important ingredients in many products, such as cosmetics and drugs for treating cancer and other diseases. This mini-review comprehensively compares the bioactivities and biological functions of biomaterials from red, green, brown, and blue-green algae. The anti-oxidative effects and bioactivities of several different crude extracts of algae have been evaluated both in vitro and in vivo. Natural products derived from marine algae protect cells by modulating the effects of oxidative stress. Because oxidative stress plays important roles in inflammatory reactions and in carcinogenesis, marine algal natural products have potential for use in anti-cancer and anti-inflammatory drugs.
“…As a consequence, antibiotic resistant and banned antibiotics have stimulated research to find effective feed additive in the world, such as herbal products, marine natural products, organic acids, microflora enhancers, probiotics, prebiotics, or combinations of these products (Engberg et al, 2000; Ayaşan and Okan, 2001, Cabuk et al, 2006; Midilli et al, 2008, Ayaşan, 2013). One of them, seaweed contains various biologically active components with different structures and functional properties (Jimenez-Escrig et al, 2011; Liu et al, 2012). In addition, the field of natural marine products have been expanded gradually (Wijesinghe and Jeon, 2012).…”
Section: Introductionmentioning
confidence: 99%
“…Bioactive components in seaweeds include polyphenols, peptides, and polysaccharides (Zhang et al, 2007; Jimenez-Escrig et al, 2011). Many of these active compounds were useful functional ingredients with numerous health benefits (Yuan and Walsh, 2006; Kim and Joo, 2008).…”
This study was conducted to investigate the effects of brown seaweed (Undaria pinnatifida) by-product and seaweed fusiforme (Hizikia fusiformis) by-product supplementation on growth performance and blood profiles including serum immunoglobulin (Ig) in broilers. Fermentation of seaweeds was conducted by Bacillus subtilis and Aspergillus oryzae. In a 5-wk feeding trial, 750 one-d-old broiler chicks were divided into 5 groups, and were assigned to the control diet or experimental diets including control+0.5% brown seaweed (BS) by-product, control+0.5% seaweed fusiforme (SF) by-product, control+0.5% fermented brown seaweed (FBS) by-product, and control+0.5% fermented seaweed fusiforme (FSF) by-product. As a consequence, body weight gain (BWG) and gain:feed of seaweed by-product groups were clearly higher, when compared to those of control diet group from d 18 to 35 and the entire experimental period (p<0.05). In mortality rate, seaweed by-product groups were significantly lower when compared to control diet group during entire experimental period (p<0.05). However, Feed Intake of experimental diets group was not different from that of the control group during the entire experimental period. Whereas, Feed Intake of fermented seaweed by-product groups was lower than that of non-fermented seaweed groups (p<0.05). Total organ weights, lipids, and glutamic oxalacetic transaminase (GOT) of all treatment groups were not different from those of control group. However, glutamic pyruvate transaminase (GPT) of all treatment groups was higher than that of control group at d 17 (p<0.05). In case of serum Igs concentration, the concentration of IgA antibody in BS, SF, FSF treatment groups was significantly higher than in control group at d 35 (p<0.01). IgA concentration in FBS supplementation groups was negligibly decreased when compared to the control group. IgM concentration in the serums of all treatment groups was significantly higher than in control group (p<0.05) and in fermented seaweed by-product groups were much higher than in non-fermented seaweed groups (p<0.05). On the other hand, IgG concentrations in all treatment groups were lower than in control group (p<0.05). Taken together, our results suggest that by-product dietary supplementation of BS, SF, FBS, and FSF in poultry may provide positive effects of growth performance and immune response.
“…Currently, the
regenerative medicine and tissue engineering application of the SP has become a hot
research area. Jiménez-Escrig et al (2011) have reviewed the vital role of SP from seaweeds in human
health.Fig. 1Seaweeds growing on the California Coast of the Pacific
OceanFig.…”
Seaweeds, being prolific sources of bioactive components have garnered
unprecedented interest in recent times. The complex polysaccharides from the brown,
red and green seaweeds possess broad spectrum therapeutic properties. Especially,
the sulfated polysaccharides, viz
.
fucans,
carrageenans and ulvans have exhibited strong antioxidant, antitumor,
immunostimulatory, anti-inflammatory, pulmonary fibrosis
anticoagulant/antithrombotic, lipid lowering, antiviral, antibacterial,
antiprotozoan, hyperplasia prevention, gastrointestinal, regenerative and nano
medicine applications. Considering the immense biomedical prospects of sulfated
polysaccharides, the profound and emerging functional properties published in recent
times will be discussed here with experimental evidences. The limitations of the
seaweed-derived sulfated polysaccharides in healthcare will be summarized.
Strategies to maximize extraction and bioavailability will be pondered.
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