Seasons of the Year and Activity of SLE and Behçet's Disease

Krause, I.; Shraga, I.; Molad, Yair; Guedj, D; Weinberger, Abraham

doi:10.3109/03009749709065715

Cited by 33 publications

(32 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In systemic lupus erythematosus (SLE) patients, an increased incidence of photosensitive skin rashes occurs predominantly in summer. A survey study found SLE patients to have more joint pain in winter and spring (12). It was reported that the onset of rheumatoid arthritis (RA) was more common in winter months, and in another RA study, pain was correlated positively with temperature and vapor pressure (13,14).…”

Section: Discussionmentioning

confidence: 99%

“…Our study is the first study to evaluate oral ulcer characteristics and their relationship with season by the patients' perspectives in the literature. Krause et al (12) found no correlation between weather conditions and disease severity of Behçet's patients except for joint symptoms, which were reported to worsen in autumn and/or spring. They found no correlation between oral ulcer exacerbations and weather/season.…”

Section: Discussionmentioning

confidence: 99%

“…We have identified only 3 previous studies that analyzed Behçet's patients' symptoms associated with weather/ season, and only 1 of them analyzed the relationship of Behçet's oral aphthous ulcers with season (12,15,16) (Table 5). Our study is the first study to evaluate oral ulcer characteristics and their relationship with season by the patients' perspectives in the literature.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Is there any relationship between season/weather and oral ulcer in Behçet’s disease?

Kaşifoğlu¹,

Korkmaz²

2014

Eur J Rheumatol

View full text Add to dashboard Cite

Objective: Some rheumatic diseases are being influenced by weather conditions. We examined the relationship between oral ulcers and weather/season in Behçet' s disease (BD) patients and evaluated the oral ulcers' characteristics by the patients' perspectives. Material and Methods:Patients with BD were evaluated using a self-questionnaire, including patients' clinical and demographical characteristics and detailed characteristics of oral ulcers and the association with season. Results:The most common site of oral ulcers was the tongue (89%). Of 90 patients, there were predisposing factors in oral ulcers. Among patients with BD, 30 believed that seasonal variation aggravated their oral ulcers, especially in winter and autumn. Conclusion:The exacerbation of oral ulcers in patients with BD may be related to the seasons. The weather changes in our study are based on the patients' impression; these should be confirmed by objective findings and clinical assessment in further studies.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Is there any relationship between season/weather and oral ulcer in Behçet’s disease?

Kaşifoğlu¹,

Korkmaz²

2014

Eur J Rheumatol

View full text Add to dashboard Cite

show abstract

“…One reported a significant increase in the European Consensus Lupus Activity Measure (ECLAM) during the spring with no worsening of disease activity during the summer (51) . Another identified a significant increase in disease activity scored by a clinical disease activity score during the winter compared to all other seasons (52) . Furthermore, another study reported increased prevalence in flares of disease activity and lupus nephritis in SLE patients from Hong Kong, during December and January, corresponding to winter (53) .…”

Section: Seasonal Variation and Disease Activity In Systemic Lupus Ermentioning

confidence: 99%

“…Some studies have shown an accumulation of photosensitivity (50,51) or a greater incidence of rash (52) during the summer months. However, lack of statistical analysis weakens these findings and the results should be interpreted with this in mind.…”

Section: Seasonal Variation and Disease Activity In Systemic Lupus Ermentioning

confidence: 99%

An evaluation of vitamin D status in individuals with systemic lupus erythematosus

et al. 2011

View full text Add to dashboard Cite

Systemic lupus erythematosus (SLE) is a multi-system inflammatory disease where genetic susceptibility coupled with largely undefined environmental factors is reported to underlie the aetiology of the disease. One such factor is low vitamin D status. The primary source of vitamin D is endogenous synthesis following exposure of the skin to UVB light. Photosensitivity, sunlight avoidance and the use of sun protection factor in combination with medications prescribed to treat the symptoms of the disease, puts SLE patients at increased risk of vitamin D deficiency. Decreased conversion of 25-hydroxyvitamin D to the metabolically active form, 1,25-dihydroxyvitamin D 3 , is possible, due to renal impairment common in SLE putting additional stress on vitamin D metabolism. The majority of studies have identified low 25-hydroxyvitamin D in SLE patients, albeit using varying cut-offs ( < 25 to < 80 nmol/l). Of these studies, fifteen have investigated a link between status and disease activity with conflicting results. Variation with disease activity index measures used alongside methodological limitations within the study design may partially explain these findings. This review discusses the importance of optimal vitamin D status in SLE, critically evaluates research carried out to date that has investigated vitamin D in SLE, and highlights the need for a well-designed observational study that controls for diet, medication use, dietary supplements, UV exposure and seasonality, that uses sensitive methods for measuring vitamin D status and disease activity in SLE to conclusively establish the role of vitamin D in SLE.

show abstract

Identification of physical and psychosocial problems based on symptoms in patients with Behçet’s disease

et al. 2019

View full text Add to dashboard Cite

The purpose of this study was to use the International Classification of Functioning, Disability and Health (ICF) to identify physical and psychosocial problems associated with symptoms of Behçet's disease (BD) in Japanese patients. Thirty patients with BD were interviewed in a pilot study using the "ICF Checklist", and a team of medical experts selected categories related to physical and psychosocial aspects of BD. To identify specific physical and psychosocial problems of Japanese patients with BD, 100 new patients were interviewed using the selected categories. Among the 128 categories in the original ICF Checklist, 80 categories were identified as impaired, and another 12 ICF categories were added based on expert discussion of patients input. The number of problem categories was significantly greater in patients with BD with eye involvement and fatigue (eye involvement, 25.7 categories; fatigue, 25.2 categories; both P < 0.001). Specifically, patients with eye involvement had more difficulties with problems in daily life, such as writing (odds ratio 4.2), understanding such nonverbal messages as gestures and facial expressions (13.7), moving (5.7), walking in intense sunlight and bright light (17.6), and patients with fatigue had more difficulties with climate problems such as symptoms getting worse at the turn of the seasons or on cold days (2.5), compared to those without these symptoms. This study demonstrated that support focusing not only on physical symptoms but on other aspects of life as well is necessary for patients with BD, particularly patients with eye involvement and fatigue.

show abstract

Seasons of the Year and Activity of SLE and Behçet's Disease

Cited by 33 publications

References 15 publications

Is there any relationship between season/weather and oral ulcer in Behçet’s disease?

Is there any relationship between season/weather and oral ulcer in Behçet’s disease?

An evaluation of vitamin D status in individuals with systemic lupus erythematosus

Identification of physical and psychosocial problems based on symptoms in patients with Behçet’s disease

Contact Info

Product

Resources

About