Seasonality in Major Depressive Disorder: Effect of Sex and Age

Fellinger, Matthäus; Waldhör, Thomas; Serretti, Alessandro; Hinterbuchinger, Barbara; Pruckner, Nathalie; König, Daniel; Gmeiner, Andrea; Vyssoki, Sandra; Vyssoki, Benjamin; Fugger, Gernot

doi:10.1016/j.jad.2021.09.051

Cited by 11 publications

(18 citation statements)

References 39 publications

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“…In line with the previous findings, 16 , 20 but opposite to the manic episode admissions, the unipolar depressive disorder admissions dropped in the summer season, followed by a rise during the period when the daylength was at its most extreme but then slowly shortening. Major seasonal peaks for unipolar depression were found in autumn and in spring.…”

Section: Discussionsupporting

confidence: 91%

“…Patient admission studies on unipolar depressive disorder have inconclusively suggested either winter seasonality or more admissions outside winter (in spring or late-autumn) or no seasonal pattern. 16 , 19 , 20 Admission rates of unipolar depressive disorder have been shown to be lower than expected in summer. 16 , 20 …”

Section: Introductionmentioning

confidence: 94%

“… 16 , 19 , 20 Admission rates of unipolar depressive disorder have been shown to be lower than expected in summer. 16 , 20 …”

Section: Introductionmentioning

confidence: 94%

“…17,18 Patient admission studies on unipolar depressive disorder have inconclusively suggested either winter seasonality or more admissions outside winter (in spring or late-autumn) or no seasonal pattern. 16,19,20 Admission rates of unipolar depressive disorder have been shown to be lower than expected in summer. 16,20 Studies on seasonal variation in schizophrenia have mostly found that admission rates are higher than expected in summer, but spring and winter peaks have also been observed.…”

Section: Introductionmentioning

confidence: 99%

“…16,19,20 Admission rates of unipolar depressive disorder have been shown to be lower than expected in summer. 16,20 Studies on seasonal variation in schizophrenia have mostly found that admission rates are higher than expected in summer, but spring and winter peaks have also been observed. [21][22][23] However, some studies have found no seasonal pattern in the schizophrenia admissions.…”

Section: Introductionmentioning

confidence: 99%

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Seasonal Effects on Hospitalizations Due to Mood and Psychotic Disorders: A Nationwide 31-Year Register Study

Törmälehto¹,

Svirskis²,

Partonen³

et al. 2022

CLEP

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Purpose To examine seasonal patterns of hospital admissions due to mood and psychotic disorders and to investigate whether the admission rates show variation according to the seasonal daylength (photoperiods). Patients and Methods A retrospective nationwide register-based cohort of all psychiatric admissions (N=978,079) during 1987–2017 in Finland was utilized. The smoothed time-series of adjusted ratio of observed and expected (O/E) daily counts were estimated to examine seasonal variation. The mean O/E with 95% confidence intervals (CI) was used to study the admission rates by photoperiods. The calendar days were classified into the 71-day photoperiods based on the daylength (long/summer, short/winter, equal/spring, equal/fall) and the pace of change in daylength (slowly/rapidly increasing/decreasing daylength). Results Manic episodes peaked in summer during the long (mean O/E=1.10, 95% CI=1.06–1.13) and slowly decreasing (1.09, 1.06–1.13) photoperiods and had a nadir in winter during the slowly increasing (0.93, 0.89–0.98) photoperiod. Admissions for unipolar depressive (UPD) episodes peaked in autumn and in spring at the end of the rapidly decreasing (1.03, 1.02–1.04) and increasing (1.03, 1.01–1.04) photoperiod, and dropped in summer during the long and slowly decreasing (0.95, 0.94–0.96) photoperiods. Bipolar depressive (BPD) and mixed episodes signaled excess admissions in autumn and in spring. Admissions for schizophrenia were higher than expected from summer to early-autumn, during the long and slowly decreasing photoperiods (1.02, 1.02–1.03), and lower than expected in other seasons, especially in mid-spring during the rapidly increasing photoperiod (0.98, 0.98–0.99). Conclusion The study indicates the seasonality and photoperiodicity of mental disorders, especially for manic episodes. The seasonal pattern is similar between schizophrenia and manic episodes, and between UPD, BPD, and mixed episodes.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 94%

“… 16 , 19 , 20 Admission rates of unipolar depressive disorder have been shown to be lower than expected in summer. 16 , 20 …”

Section: Introductionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Seasonal Effects on Hospitalizations Due to Mood and Psychotic Disorders: A Nationwide 31-Year Register Study

Törmälehto¹,

Svirskis²,

Partonen³

et al. 2022

CLEP

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Changes in anxiety and depression symptoms during the Covid-19 lockdown in the Netherlands. The moderating role of pre-existing mental health, employment situation and alcohol consumption

Mangot-Sala

Smidt

Liefbroer

2023

Soc Psychiatry Psychiatr Epidemiol

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Purpose Evidence suggests an increase of depression and anxiety symptoms during the Covid-19 pandemic but most studies relied on cross-sectional designs and/or small samples, and they often overlooked subgroup effects in the impact of the lockdown. We investigated the effect of the pandemic on depression and anxiety symptoms, and whether it differed by employment situation and alcohol consumption. Methods This longitudinal study used 23 waves of the Covid-Questionnaire (April 2020—July 2021), within the Lifelines cohort from the Netherlands (n = 76,254). Depression and anxiety symptoms were combined in a “mental health score”. Linear fixed-effects models were fitted to analyse trends in mental health throughout the observation period. The moderating role of pre-existing mental health, employment situation, and alcohol consumption was tested. Results Depression and anxiety symptoms fluctuated considerably during the observation period, with clear peaks in winter 2021, during the strictest lockdown period. Moreover, temporal patterns differed by employment situation and alcohol consumption patterns, suggesting that various subgroups reacted to the pandemic and the lockdown in different ways. Conclusion Lockdowns increased depression and anxiety symptoms in the Netherlands. The effect was particularly strong for unemployed individuals, those with risky alcohol consumption patterns and those with pre-existing mental health disorders.

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Depressive Disorder Related Hospitalizations in Portugal Between 2008–2015: a Nationwide Observational Study

2022

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Seasonality in Major Depressive Disorder: Effect of Sex and Age

Cited by 11 publications

References 39 publications

Seasonal Effects on Hospitalizations Due to Mood and Psychotic Disorders: A Nationwide 31-Year Register Study

Seasonal Effects on Hospitalizations Due to Mood and Psychotic Disorders: A Nationwide 31-Year Register Study

Changes in anxiety and depression symptoms during the Covid-19 lockdown in the Netherlands. The moderating role of pre-existing mental health, employment situation and alcohol consumption

Depressive Disorder Related Hospitalizations in Portugal Between 2008–2015: a Nationwide Observational Study

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