Seasonal Variations of Daily Changes in Blood Pressure Among Hypertensive Patients with End-Stage Renal Diseases

Abstract

Hypertension is a well-known cardiovascular risk. Patients with end-stage renal diseases frequently suffer hypertension, and their blood pressure elevates in winter. However, seasonal changes in daily variations of blood pressure are poorly assessed in patients treated with hemodialysis. Thirty hypertensive patients with end-stage renal diseases were enrolled in the study. Dry weight and antihypertensive medications were altered when they were necessary. Home blood pressure measurements were performed at least for 1 week in each season; April-May 2008, July-August 2008, October-November 2008, and January-February 2009. Both morning and evening systolic blood pressures (SBPs) showed significant seasonal changes ( p < 0.01), with the highest blood pressure in winter (162 +/- 18 and 135 +/- 22 mmHg in morning and evening). Morning diastolic blood pressure (DBP) also exhibited seasonal changes ( p < 0.05), with the highest blood pressure in fall ( 78 +/- 8 mmHg). Evening DBP did not manifest seasonal deviations. Morning-evening differences in SBP and DBP were the greatest in winter (28 +/- 21 and 10 +/- 9 mmHg in SBP and DBP, p < 0.01), and the smallest in summer (16 +/- 12 and 6 +/- 5 mmHg). Daily variations of SBP and DBPs in spring (19 +/- 12 and 7 +/- 6 mmHg) and fall (20 +/- 13 and 9 +/- 8 mmHg) were between those of summer and winter. Our results indicate that not only averaged blood pressure but also variations of blood pressure in winter are larger than the other seasons, and suggest that these blood pressure variations participate in cardiovascular events in hypertensive patients with end-stage renal diseases.

Variações Meteorológicas E as Alterações De Pressão Arterial Dos Pacientes Em Hemodiálise: Revisão Sistemática

“…Dos dezoito estudos realizados com pacientes em hemodiálise, dezesseis encontraram associação entre as variáveis meteorológicas e a pressão arterial, sendo a mais citada a temperatura do ar. Em quinze artigos as associações foram inversas, aumento da pressão arterial com a diminuição da temperatura do ar ou diminuição da pressão arterial ao aumento da temperatura do ar (ARGILÉS, MOURAN e MION, 1998;DE CASTRO et al, 1998;TOZAWA et al, 1999;SPÓSITO, NIETO E VENTURA, 2000;CHEUNG et al, 2002;ARGILÉS et al, 2004;ARGANI e JAVANSHIR, 2004;HWANG;WANG;CHIEN, 2007;TAKENAKA et al, 2010;USVYAT et al, 2012;GUINSBURG et al, 2015;BROERS et al, 2015;DURANTON et al, 2018 b).…”

“…Os climas nos quais foram encontradas associações inversas entre a temperatura do ar e pressão arterial foram: Mediterrâneo (Europa e América do Norte) (ARGILÉS, MOURAN e MION, 1998;ARGILÉS et al, 2004;USVYAT et al, 2012), Tropical (América do Sul, Ásia a África) (DE CASTRO et al, 1998;HWANG;WANG;CHIEN, 2007;AJIYAN et al, 2012), Subtropical (América do Norte e América do Sul) (SPÓSITO, NIETO E VENTURA, 2000;USVYAT et al, 2012), Continental (América do Norte e Ásia) (USVYAT et al, 2012;TOZAWA et al, 1999), Semiárido (Ásia) (ARGANI e JAVANSHIR, 2004) e Temperado (América do Norte e Ásia) (CHENG et al, 2002;TAKENAKA et al, 2010).…”

“…Dois estudos a média foi abaixo do geral (45-46 anos) no Brasil (DE CASTRO et al, 1998) e na Polônia (WYSTRYCHOWSKI et al, 2005). Em seis estudos a média de idade foi acima de 60 anos (FINE 2000;TAKENAKA et al, 2010;USVYAT et al, 2012;BROERS et al, 2015;DURANTON et al, 2018 b).…”

“…Kovacic e Kovacic (2004) que também não encontraram associações, todos os pacientes eram anúricos. Takenaka et al (2010) todos os participantes eram hipertensos em uso de medicamentos anti-hipertensivo.…”

Seasonal fluctuation of erectile dysfunction: A cross‐sectional study from a tertiary university hospital across 10 years

“…(AMI), heart failure (HF), acute coronary syndrome (ACS) and atrial fibrillation (AF) reach peak levels in the winter months (Stewart et al, 2017). Similarly, some studies also indicate that blood glucose levels, haemoglobin A 1C (HbA 1C ) and blood pressure values vary statistically significant seasonally, especially for winter (Kim et al, 2014;Modesti et al, 2018;Ryu et al, 2014;Takenaka et al, 2010).…”