Seasonal variations in dermatologic and dermatopathologic diagnoses: a retrospective 15‐year analysis of dermatopathologic data

Harvell, Jeff D.; Selig, Daniel J.

doi:10.1111/ijd.13229

Cited by 13 publications

(4 citation statements)

References 17 publications

(22 reference statements)

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“…Clinical observations pointed to the same pattern in psoriasis with deterioration or first episodes starting mainly in cold months [12][13][14]. This pattern was not however observed by all authors, citing multifactorial nature of the disease [15,16]. Recently, a review on seasonal variation of psoriasis in Northern and Central Europe revealed that 50% of patients showed no difference in the severity of their…”

Section: Introductionmentioning

confidence: 85%

Does the effectiveness of biological medications in the treatment for psoriasis depend on the moment of starting therapy? A preliminary study

Niedźwiedź,

Noweta,

Narbutt

et al. 2024

pdia

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Introduction It is well known that biological medications acting on selected elements of the immune response are highly effective in psoriasis treatment. It is a common perception that psoriasis is a seasonal disorder with improvement in warmer months, however it has not been unequivocally confirmed. It is not known whether the time of year of starting systematic therapy for psoriasis influences treatment outcomes. Material and methods Changes in psoriasis severity scores during treatment with biologics were investigated. The scores were recorded for 62 patients with moderate to severe psoriasis at the beginning, after 1, 4 and 7 months of the therapy. Patients were divided into two groups: those beginning the treatment in the cold period of the year (November-March) and in the warm period (May-September). The seasonal groups were also divided into subgroups according to the type of biologics used: interleukin inhibitors and tumor necrosis factor α (TNF-α) inhibitors. Results of the treatment were analysed using standard statistical tests of differences between samples. Results After 1 and 4 months of the therapy, better efficacy of interleukin inhibitors was found in patients starting treatment in summer. The course of psoriasis improvement in patients taking TNF-α inhibitors resulted in consistent improvement regardless of the season. The outcome of the treatment after 7 months was similar for both seasonal groups and types of biologics used. Conclusions Our understanding of the effectiveness of the treatments depending on the time of the year combined with the type of biologics used, may further improve results of the therapy.

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Section: Introductionmentioning

confidence: 85%

Does the effectiveness of biological medications in the treatment for psoriasis depend on the moment of starting therapy? A preliminary study

Niedźwiedź,

Noweta,

Narbutt

et al. 2024

pdia

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“…[ 11 ] While countries with tropical and subtropical climatic conditions (Taiwan, Singapore, Malaysia) had two peaks in a year, those with higher latitudes (South Korea, Japan, Finland, United States) showed a single yearly peak of the disease. [ 7 9 70 71 72 73 74 75 ] Similarly, Finland generally had experienced peaks in early autumn. [ 71 ] We also noted almost similar epidemiological trends for major outbreaks during summers and rainy seasons (April to September), and small outbreaks during autumn (October-November) and winter (December-January) months over these years across India having varied topography, geography and climatic conditions.…”

Section: Discussionmentioning

confidence: 99%

Hand, Foot and Mouth Disease

Sharma

Mahajan

Mehta

et al. 2022

Indian Dermatology Online Journal

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Background: There have been sporadic and periodic large-scale epidemics of hand, foot, and mouth disease (HFMD) with cases at risk for significant morbidity and mortality particularly in Southeast Asia since 1997 and in India since early 2003. Method: We retrospectively studied 403 cases recorded from 2009 to 2019 and reviewed relevant Indian literature published between 2004 and 2019 to understand clinical, epidemiological, and virological attributes of this long-lasting Indian epidemic. Result: There were 96.8% children and adolescents (M:F 1.6:1) aged 2 months to 18 years and 84% were aged <5 years. Adult family contacts comprised 3.2%. Only 12 sporadic cases occurred during 2009-2011 followed by increased number from 2012 to 2015 peaking with 30.8% cases in 2013 and declining slowly until the year 2019 with small resurge in 2018. The major peaks occurred during summers with small peaks in autumns. Literature review showed 3332 cases presenting between 2004 and 2019 across Indian states with similar epidemiological trends whereas serotyping identified Coxsackievirus A16 (CV A16) in 83%, Coxsackievirus A6 (CV A6) in 17%, Enterovirus 71 in 4.1%, and multiple strains in 11.7% samples, respectively. Conclusion: The overall features of this long-lasting HFMD epidemic; affecting children aged <5 years more often than adults, none or minimum neurological or pulmonary complications in few patients, peaks occurring during summer and autumn months, and identity of the pathogenic virus coincide with global trends. However, the continuous spread of the disease across the country appears in sync with pre-epidemic periods of China and Taiwan. It calls for a continuous surveillance and making HFMD a notifiable disease in India.

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“…Although most commonly found in the Central and South American population, ashy dermatosis demonstrates a worldwide prevalence [2][3][4][5]. Ashy dermatosis can appear at any season of the year in patients of any age group or gender [2,6]. Although primarily a cosmetic issue, its prevalence and prominent appearance in dark skinned individuals can be very troubling for patients.…”

Section: Introductionmentioning

confidence: 99%