Seasonal Variations and Trends in Concentrations of Filter-collected Polycyclic Aromatic Hydrocarbons (PAH) and Mutagenic Activity in the San Francisco Bay Area

Atmospheric Polycyclic Aromatic Hydrocarbons at a Point Source of Emissions. Part A: Identification and Determination of Polycyclic Aromatic Compounds in Airborne Particulate Matter Near a Horizontal Stud Soderberg Plant

“…4 Since 1985, B[a]P has been analyzed on the particulate on the filters of Hi-Vol samplers. The sampling protocol is similar to that published recently by Flessel et al 7 The filters (Gelman Type A/E) are pre-calcined at 400°C to eliminate organic contamination. Sampling is done at a standard flow rate of 1.14 m 3 /min (40 SCFM).…”

Polycyclic Aromatic Hydrocarbon Levels and Mutagenic Activities of Organic Extracts from Airborne Particles in Santiago de Chile

“…Mutagenic response (revertants -irr3) induced in the strain TA 98 of S. typhimurium in the presence (+S9) and in the absence of S9 (-S9) by organic extracts from airborne particulate samples in downtown Santiago tant consequences for human health because it is the most potent PAH carcinogen [1], The annual mean concentra tion of particulate-associated benzo(a)pyrene found in downtown Santiago was 18.24 ng-nr3 (range 2.08-130.3 ng-m-3) considerably higher than the values reported from other studies. To give examples: four cities in the UK have reported benzo(a)pyrene concentrations from 0.2 to 1.4 ng-m-3 [25], values for London have been reported as 0.18-5.94 ng-nr3 [17], for Munich and Nu remberg 2.11-3.47 ng-nr3 [26], for Stockholm 0.1-2.2 ng-m-3 [27], for Paris 1-4.8 ng-m-3 [28], and for Califor nia 0.2 ng-m-3 as an annual mean [21].…”

Polycyclic Aromatic Hydrocarbon–DNA Adducts and Breast Cancer: A Pooled Analysis

“…Also, we noted a higher OR among women with blood collected during the winter months-a season that others have associated with high BaP air concentration measurements. 27 The OR for breast cancer and adducts also varied somewhat with intake of PAHcontaining foods, regardless of the measure used, with a reduced OR for those in the lowest quantile of intake and an elevated OR for all other levels of intake. The inconsistent pattern of the ORs across varying levels of PAH exposure confirms that the detection of PAH-DNA adducts may not be associated with higher levels of exposure, 28 but may instead identify subjects particularly susceptible to the effects of PAH.…”