Seasonal variation of bioactive components in Valeriana jatamansi from Himachal Pradesh, India

Singh, Randhir; Gopichand,; Meena, Ramjee Lal; Sharma, Bhawna; Singh, Bikram; Kaul, Vijay Kumar; Ahuja, Paramvir Singh

doi:10.1016/j.indcrop.2010.05.006

Cited by 38 publications

(25 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Guaiene epoxide was recorded higher in winter season (11.5%) as compared to summer and spring season, while, seychellene, α-patchoulene, the reported value in the same species (16). However, results are contrary with Singh et al (21) who reported summer season (May-June) best for essential oil yield in V. Jatamansi. Comparatively, lower yield in spring season in this study, might be attributed to the fact that the species starts flowering and resource allocation is largely utilized in flower development.…”

Section: Essential Oil Yieldmentioning

confidence: 60%

Essential oil composition and antioxidant activity in Valeriana jatamansi Jones: influence of seasons and growing sources

Rawat

Jugran

Bhatt

et al. 2016

Journal of Essential Oil Research

View full text Add to dashboard Cite

d a G. B. Pant institute of himalayan Environment and Development, Kosi-Katarmal, almora, uttarakhand, india; b school of Environment and natural resources, Doon university, Dehradun; c Department of Botany, hamdard university (Jamia hamdard), new Delhi; d Guru Govind singh indraprastha university, Dwaraka, new Delhi ABSTRACTValeriana jatamansi is a perennial medicinal herb used in traditional and modern medicines for preventing number of diseases. Root samples were collected from wild and cultivated conditions in different seasons (spring, summer and winter) and analyzed for essential oil composition using gas chromatography -Mass spectrometry (GC-MS). Antioxidant activity of essential oil was evaluated using DPPH (1, 1-Diphenyl-2-picrylhydrazyl radical) assay. A total of thirty compounds (constitutes 80.1-92.1% of total essential oil) were detected by GC-MS analysis. Patchouli alcohol (36.6-52.8%) was recorded as a major compound followed by guaiene epoxide (3.6-11.5%), seychellene (4.2-5.6%), α-guaiene (2.2-4.6%), kessane (2.7-3.6%), α-patchoulene (0.1-2.3%), β-selinene (0.8-3.1 β-acoradienol (0.6-2.4%), ar-curcumene (0.7-2.2%), γ-patchoulene (1.4-2.6%), viridiflorol (0.6-2.4%), and α-humulene (0.1-4.6%). Essential oil content was recorded higher during winter season in wild (0.9%) and cultivated plants (0.8%) as compared to other seasons. Antioxidant activity of essential oil measured by DPPH radical activity assay varied (IC 50 = 117.5-227.6 μL/mL) among seasons and growing conditions. Winter season is recommended for maximum essential oil yield and spring season for antioxidant activity.

show abstract

Section: Essential Oil Yieldmentioning

confidence: 60%

Essential oil composition and antioxidant activity in Valeriana jatamansi Jones: influence of seasons and growing sources

Rawat

Jugran

Bhatt

et al. 2016

Journal of Essential Oil Research

View full text Add to dashboard Cite

show abstract

“…Several valepotriate compounds and their analogues, namely, acetovaltrate ( 129 ), 8, 11‐desoidodidrovaltrate ( 130 ), desoxidodidrovaltrate ( 131 ), isovaltrate isovaleroyloxyhydrin ( 132 ), 1,5‐dihydroxy‐3,8‐epoxyvalechlorine ( 133 ), rupesin E ( 134 ), didrovaltrate acetoxy hydrin ( 135 ), 10‐acetoxyvaltrathydrin ( 136 ), isovaleroxyhydroxy‐didrovaltrate (IVHD‐valtrate) ( 137 ), 5‐hydroxydidrovaltrate ( 138 ), (3S,4R,5S,7S,8S,9S)‐3,8‐epoxyoctahydro‐4,8‐dimethylcyclopenta[ c ]pyran‐7‐ol ( 139 ), (3S,4S,5S,7S,8S,9S)‐3,8‐epoxy‐7‐hydroxy‐4,8‐dimethylperhydrocyclopenta[ c ]‐pyran ( 140 ), 4,7‐dimethyloctahydrocyclopenta[ c ]pyran ( 141 ), hexahydro‐6‐hydroxy‐7‐(hydroxymethyl)‐4‐methylenecyclopenta[ c ]pyran‐1(3 H )‐one ( 142 ), (4β,8β)‐8‐methoxy‐3‐methoxy‐10‐methylene‐2,9‐dioxatricyclo[4.3.1.0 3,7 ]decan‐4‐ol ( 143 ), isovalerate isovaleroxyhydrin ( 144 ), and homoisovaltrate ( 145 ) were also studied. Furthermore, significantly higher valepotriates content was reported in the rhizome of V. jatamansi growing in different conditions during January, October, and November months (Singh et al, ).…”

Section: Valepotriatesmentioning

confidence: 97%

Valeriana jatamansi: An herbaceous plant with multiple medicinal uses

Jugran

Rawat

Bhatt

et al. 2019

Phytotherapy Research

View full text Add to dashboard Cite

Valeriana jatamansi Jones (Family: Caprifoliaceae), a high value medicinal plant, was distributed in many countries of Asia. The species possesses important valepotriates and is a good source of flavones or flavone glycosides, lignans, sesquiterpenoids or sesquiterpenoid glycoside, bakkenolide type sesquiterpenoids, phenolic compounds, terpinoids, etc. The use of the species in traditional and modern medicines is well known. For instance, V. jatamansi is very important for its insect repelling and antihelmethic properties. Similarly, sedative, neurotoxic, cytotoxic, antidepressant, antioxidant, and antimicrobial activities of the species in various ailments in the indigenous system of medicine, particularly in Asia, are reported. This review focuses on the detailed phytochemical composition, medicinal uses, and pharmacological properties of V. jatamansi along with analysis of botanical errors in published literature and reproducibility of the biomedical researches on this multipurpose herbaceous species.

show abstract

“…Valepotriates (class of iridoid alkaloids from Valeriana sp.) and valerenic acid derived from the roots/rhizomes of V. jatamansi and other related species of the genus are considered constitute the chemical fingerprint of these species and are used for assuring the quality of the plants (Singh et al 2006(Singh et al , 2010. In the Indian Himalayan Region, the species is widely distributed at an altitude from 1,000 to 3,000 m a.s.l.…”

Section: Introductionmentioning

confidence: 99%

“…It is imperative to identify elite plants/populations based on their chemical attributes to ensure the quality of the plant material. V. jatamansi plants are noted for their high content of valerenic acid, the main active constituent of valerian, and high antioxidant activity (Singh et al 2010;Bhatt et al 2012;. Valerenic acid is considered to be the chemical fingerprint of the V. jatamansi plant and has been reported to possess sedative and antispasmodic properties (Houghton 1999).…”

Section: Introductionmentioning

confidence: 99%

Identification of ISSR markers associated with valerenic acid content and antioxidant activity in Valeriana jatamansi Jones in the West Himalaya

2015

View full text Add to dashboard Cite

Valeriana jatamansi Jones, commonly known as Indian Valerian or Tagar (Family: Valerinaceae) is used in both traditional and modern systems of medicine. The plants of this species are known for their high content of valerenic acid, the main active constituent of valerian, and high antioxidant activity, and these characteristics have increased the demand for these plants by the pharmaceutical industry. At present, the demand for planting material is largely met from the harvesting of wild plants, which vary in quality and quantity of the active ingredient. Therefore, there is a need to identify individual plants/populations with a higher content of the active ingredients and higher antioxidant activity. We used inter-simple sequence repeats (ISSR) markers in 151 genotypes of 25 V. jatamansi populations to identify markers associated with valerenic acid and antioxidant activity. Of the 130 ISSR primers tested, 20 generated 159 bands, with an average of 7.95 bands per primer. Valerenic acid content was significantly (p \ 0.05) higher in the Katarmal (aerial portion 0.57 ± 0.04 %) and Joshimath populations (root portion 1.80 ± 0.12 %). Antioxidant activity using these different in vitro assays varied among the populations and plant portions, with maximum antioxidant activity found in the aerial plant portion (8.63 ± 0.06 mM) and roots [8.36 ± 0.0 mM ascorbic acid equivalents (AAE)/100 g dry weight (dw)] of the Didihat and Katarmal populations, respectively, using the ABTS [2, 2 0 -azino-bis(3-ethylbenzothiazoline-6-sulphonic)] assay. The DPPH (2, 2-diphenyl-1-picryylhydrazyl free radical scavenging) assay revealed maximum antioxidant activity in the aerial plant portion (15.23 ± 0.09 mM) and roots (17.53 ± 0.04 mM AAE/100 g dw) of the Didihat population. The FRAP (ferric-reducing antioxidant power) assay showed that the roots of plants of the Ukhimath population had significantly higher antioxidant activity (12.71 ± 0.04 mM AAE/100 g dw) than those of other populations of V. jatamansi. Based on the stepwise multiple regression analysis, seven positive and six negative markers showed significant association with valerenic acid content. Antioxidant activity measured by the ABTS, DPPH and FRAP assays showed a positive correlation with 14, 13 and 10 markers, respectively (p \ 0.001). These markers have the potential for application in breeding programmes in order to select lineages of V. jatamansi with higher biochemical attributes, especially when no other genetic information, such as linkage maps and quantitative trait loci is available.Electronic supplementary material The online version of this article (

show abstract

Seasonal variation of bioactive components in Valeriana jatamansi from Himachal Pradesh, India

Cited by 38 publications

References 5 publications

Essential oil composition and antioxidant activity in Valeriana jatamansi Jones: influence of seasons and growing sources

Essential oil composition and antioxidant activity in Valeriana jatamansi Jones: influence of seasons and growing sources

Valeriana jatamansi: An herbaceous plant with multiple medicinal uses

Identification of ISSR markers associated with valerenic acid content and antioxidant activity in Valeriana jatamansi Jones in the West Himalaya

Contact Info

Product

Resources

About