Seasonal variation in (δ minolaevulinate synthase and porphyrin content in the harderan gland of the female golden hamster (mesocricetus auratus)

Thompson, George G.; Payne, A. P.; McGadey, J

doi:10.1016/0020-711x(80)90137-8

Cited by 17 publications

(3 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has been proposed as a potential source of pheromones (hamster: Payne, 1977; Mongolian gerbil: Thiessen et al, 1976). The gland may be involved in reproduction (Reiter and Klein, 1971;Payne et al, 1977;Shirama, 1978;Shirama et al, 1981;Moore et al, 1980).…”

Section: Discussionmentioning

confidence: 99%

Development of harderian gland during metamorphosis in anurans

Shirama¹,

Kikuyama

Takeo³

et al. 1982

Anat. Rec.

View full text Add to dashboard Cite

Development of Harderian gland of larvae of Rana japonica, Bufo bufo japonicus, and Xenopus laevis was studied. In the adult animals, well-developed Harderian glands were invariably present in the orbit. In Rana and Bufo, the gland first appeared at late prometamorphic stage and in Xenopus it appeared around climax stage. In thyroidectomized tadpoles of Bufo and Rana, the Harderian gland was induced by thyroxine. In hypophysectomized tadpoles of Bufo the gland developed when they were treated with thyroxine or TSH.

show abstract

Section: Discussionmentioning

confidence: 99%

Development of harderian gland during metamorphosis in anurans

Shirama¹,

Kikuyama

Takeo³

et al. 1982

Anat. Rec.

View full text Add to dashboard Cite

show abstract

“…In the female gland, only type A cells are present, and the lumina contain solid accretions of porphyrin which are wholly absent in the male. The porphyrin of the Harderian gland in the female alters with the reproductive phase (Payne, McGadey, Moore & Thompson, 1977a, 1979Moore, Thompson, Payne & McGadey, 1980). Moreover, castration of the male hamster results in the loss of one cell type together with greatly increased porphyrin production, these changes being prevented by a variety of androgens (Hoffman, 1971; Payne, McGradey, Moore & Thompson, 19776).…”

Section: Introductionmentioning

confidence: 94%

Influences of Some Endocrine Glands and of Hormone Replacement on the Porphyrins of the Harderian Glands of Mice

Shirama¹,

Furuya²,

Takeo³

et al. 1981

Journal of Endocrinology

View full text Add to dashboard Cite

There are marked sex differences in the Harderian gland of the C3H/He strain of mice. Female (but not male) glands contain large amounts of porphyrin, which are readily visible as solid depositions within the lumina. The histology and porphyrin content of the Harderian gland were examined in intact and in pregnant mice and in mice subjected to combinations of adrenalectomy, gonadectomy and administration of sex steroid hormones. In male mice, castration approximately doubled the amount of porphyrin in the Harderian gland. Castration plus adrenalectomy increased the levels over 30-fold, to levels similar to those found in female mice, although adrenalectomy alone produced no significant effect. Administration of testosterone to the male mice which had been castrated and adrenalectomized prevented the increases while progesterone treatment produced further increases in porphyrins. In intact females, the amount of porphyrin varied with the phase of the oestrous cycle; being lowest during metoestrus and highest during dioestrus. In ovariectomized-adrenalectomized females, the effects of administered sex hormones on the amount of porphyrin in the gland were the same as in males. In pregnant mice, the level was no significantly different from that in intact oestrous animals.

show abstract

“…Most attention has been focused on the difference of the porphyrin concentration in male and female glands Wetterberg, 1973, 1976;Moore et al, 1977Moore et al, ,1980Payne et al, 1979). Porphyrin is an important material in this gland, of course, but the major secretory material is lipid, and the lipid content in this gland is around 20% of the wet tissue weight.…”

Section: Introductionmentioning

confidence: 98%