Seasonal Variation and Dengue Burden in Paediatric Patients in New Delhi

M, Roy; Gupta, Rishein; Chopra, Nidhi; Meena, Satish Kumar; Aggarwal, Kailash Chandra

doi:10.1093/tropej/fmx077

Cited by 5 publications

(8 citation statements)

References 12 publications

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“…This evidence is also supported by the results of a study conducted in Indonesia during the period of 2014 -2018 which shows that there is a correlation between relative humidity and DHF incidence, which is statistically significant (r = 0.413, p= 0.001) (Arsin et al, 2020). This is also supported by a Sri Lankan study, Bangladesh study, three Indonesian studies, Indian study and an Thailand study ; (Islam et al, 2021;Jat & Mala, 2017) (Roy et al, 2018) Tosepu et al, 2018(Ummi Khairunisa & Wahyuningsih, 2018;Salim & Syairaji, 2020;Tosepu, Tantrakarnapa, Worakhunpiset, & Nakhapakorn, 2018).…”

Section: Impact Of Humidity On Denguesupporting

confidence: 61%

“…Muurlink et al,2018 have revealed that the best predictors of an dengue outbreak are the number of rainy days in the preceding two months (Muurlink, Stephenson, Islam, & Taylor-Robinson, 2018). According to studies conducted in Indonesia and India, there is a significant association between cumulative rainfall (Ali et al, 2020;Arcari & Tapper, 2017;Arcari, Tapper, & Pfueller, 2007;Joshua, Kaliaperumal, Krishnamurthy, Muthusamy, Venkatachalam, Gowri, Shete, Ramasamy, Gupta, Murhekar, et al, 2020;Riyanto et al, 2020;Roy et al, 2018;Salamah et al, 2012). A significant weak correlation between higher rainfall and incidence of DHF cases has been found in two studies conducted in Indonesia (Haryanto, 2016); (Salim & Syairaji, 2020).…”

Section: Impact Of Rainfall On Denguementioning

confidence: 99%

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How Do Climate Variables Affect the Transmission of Dengue Infection in South and Southeast Asia: A Scoping Review

Fernando

R.M

2023

Asian J. Interdicip. Res.

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Introduction: Dengue is an arboviral infection, transmitted from person to person via mosquito vectors. Dengue transmission is affected by rainfall, temperature, humidity and wind speed. These climate variables are changing as a result of anthropogenic climate change, and it is expected that this will affect the incidence of dengue. This scoping review explored the impacts on dengue transmission of variation in these climate variables in 12 Asian countries located in South- and South-East Asia regions. Methods: The protocol developed by the Joanna Briggs Institute was followed for this scoping review. Articles were found using the PubMed, Scopus, and Embase databases, as well as grey literature. Studies conducted in India, Bangladesh, Bhutan, the Democratic Republic of Korea, Indonesia, Maldives, Myanmar, Nepal, Thailand, Sri Lanka, and Timor Leste and published in English between 2002 and 2022 were included. An extensive literature search was conducted in February and March, 2022. A modified checklist designed for assessing the quality of ecological studies was used to assess the quality. Following quality assessment, ninety articles were included in the review. Results: The initial search yielded 1912 articles. After the duplicates were removed, 983 were identified as potentially relevant. Following the exclusion of 729 articles by two reviewers, 254 articles were subjected to full text screening. Thereafter, 90 articles were selected for the review that strictly met the inclusion criteria. Although the results were mixed, we found that dengue transmission decreases in temperature extremes. Dengue transmission increases with heavy rainfall, with a 1- 3-month lag. Humidity was also found to be related to dengue transmission. Other factors found to be associated with dengue transmission include the hours of sunshine and wind speed. Conclusion: There is a complex relationship between changing climate parameters and dengue incidence in Asia. This reflects the complex ecology of vector-borne diseases and suggests that the impact of changes in climate variables on dengue transmission may vary according to local climate and other factors.

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Section: Impact Of Humidity On Denguesupporting

confidence: 61%

Section: Impact Of Rainfall On Denguementioning

confidence: 99%

How Do Climate Variables Affect the Transmission of Dengue Infection in South and Southeast Asia: A Scoping Review

Fernando

R.M

2023

Asian J. Interdicip. Res.

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“…Several outbreaks of DF have been reported over the past 2 decades 17 , 18 , 19 , 20 , 21 , 22 , 23 and a seasonal trend during the monsoon period has been noted 24 due to the warm environment and high relative humidity 25 favoring vector growth. The reported case fatality rate shows a declining trend 26 from 6–9% 17 , 18 , 27 to 0% 23 attributable to increased awareness and better case diagnosis and management.…”

Section: Discussionmentioning

confidence: 99%

“…10 Several studies have previously analyzed the clinico-epidemiologic profile of dengue infection. 11 , 12 , 13 In this study we evaluated patients with dengue presenting to the outpatient or emergency departments of a tertiary care hospital in an urban setting for their clinical and hematological profile, management and outcomes.…”

Section: Introductionmentioning

confidence: 99%

Clinical and Hematological Profile of Patients With Dengue Fever at a Tertiary Care Hospital – An Observational Study

Tewari¹,

Tewari²,

Mehta³

2018

Mediterr J Hematol Infect Dis

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BackgroundDengue is a major health issue with seasonal rise in dengue fever cases imposing an additional burden on hospitals, necessitating bolstering of services in the emergency department, laboratory with creation of additional dengue fever wards.ObjectivesTo study the clinical and hematological profile of dengue fever cases presenting to a hospital.MethodsPatients with fever and other signs of dengue with either positive NS1 antigen test or IgM or IgG antibody were included. Age, gender, clinical presentation, platelet count and hematocrit were noted and patients classified as dengue fever without warning signs (DF) or with warning signs (DFWS), and severe dengue (SD) with severe plasma leakage, severe bleeding or severe organ involvement. Duration of hospitalization, bleeding manifestations, requirement for platelet component support and mortality were recorded.ResultsThere were 443 adults and 57 children between 6 months to 77 year age. NS1 was positive in 115 patients (23%). Fever (99.8%) and severe body ache (97.4%) were the commonest presentation. DF was seen in 429 (85.8 %), DFWS in 55 (11%), SD with severe bleeding in 10 (2%) and SD with severe plasma leakage in 6 cases (1.2%). Outpatient department (OPD) treatment was needed in 412 (82%) and hospitalization in 88 (18%). Intravenous fluid resuscitation was needed in 16 (3.2%) patients. Thrombocytopenia was seen in 335 (67%) patients at presentation. Platelet transfusion was needed in 46 (9.2%). Packed red blood cell (PRBC) transfusion was given in 3 patients with DFWS and 10 of SD with severe bleeding. Death occurred in 3 patients of SD with severe plasma leak and 2 patients with SD and severe bleeding.ConclusionsMajority of DF cases can be managed on OPD basis. SD with severe bleeding or with severe plasma leakage carries high mortality. Hospitals can analyze annual data for resource allocation for capacity expansion.

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“…This trend can be explained because of high relative humidity and warm environment which helps the growth of vector. 12 The varied clinical presentation of dengue has made clinical diagnosis difficult. Hence, the responsibility or burden of diagnosing dengue cases depends on standard and well equipped laboratory.…”

Section: Discussionmentioning

confidence: 99%

Magnitude, Seasonal-variation, Serological and Hematological Profile of Dengue in a Tertiary Teaching Hospital, Karwar, India

Kukanur¹,

Naveen²,

Chitrabanu³

et al. 2021

J. Pure Appl. Microbiol.

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Dengue viral infection is the most widely spread arbo-viral disease in Indian subcontinent. High index of clinical suspicion especially during its peak season can be rewarding in diagnosing as well as early case management of anticipated DHF and DSS cases. To estimate the magnitude, seasonal-variation, serological as well as hematological aspects of dengue cases. This was a prospective observational study held in Microbiology and Hematology laboratories of our hospital for duration of one year from July-2019 to June-2020. All the suspected dengue cases were subjected to NS1-antigen, IgM and IgG antibody detection. The samples were also tested for platelet count, total count, haematocrit as well as hemoglobin estimation. All 1,550 dengue suspected cases were subjected to serological testing, among which 157 (10.1%) were positive. The most affected populations were the adult male. As the study was conducted for one year, we could observe the seasonal trend which peaked during post-monsoon. Out of 157 cases, 81.5%, 0.6% and 17.8% were determined as primary, secondary and old dengue cases respectively. There was a significant association between NS1 antigen and fever of </= 5 days duration with ‘p’ value< 0.00001. Thrombocytopenia, leucopenia and increased haematocrit were witnessed in 15.9%, 28.6% and 35% respectively. Our study shows that we had a high magnitude of primary cases that are prone to secondary dengue infection which might have a catastrophic effect giving rise to DHF, DSS or SD.

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Seasonal Variation and Dengue Burden in Paediatric Patients in New Delhi

Abstract: Weather parameters seem to influence magnitude of dengue epidemic, particularly in dengue season. There is need to have an in-depth study about developing a prediction model for dengue epidemic.

Cited by 5 publications

References 12 publications

How Do Climate Variables Affect the Transmission of Dengue Infection in South and Southeast Asia: A Scoping Review

How Do Climate Variables Affect the Transmission of Dengue Infection in South and Southeast Asia: A Scoping Review

Clinical and Hematological Profile of Patients With Dengue Fever at a Tertiary Care Hospital – An Observational Study

Magnitude, Seasonal-variation, Serological and Hematological Profile of Dengue in a Tertiary Teaching Hospital, Karwar, India

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