Seasonal patterns of Asthma medication fills among diverse populations of the United States

Turi, Kedir N.; Gebretsadik, Tebeb; Lee, Rees L.; Hartert, Tina V.; Evans, Amber; Stone, Cosby A.; Sicignano, Nicholas; Wu, Ann Chen; Iribarren, Carlos; Butler, Melissa G.; Mitchel, Edward F.; Morrow, James; Larkin, Emma K.; Wu, Pingsheng

doi:10.1080/02770903.2017.1362426

Cited by 11 publications

(4 citation statements)

References 21 publications

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“…Such seasonal patterns have also been demonstrated by Turi et al for asthma medication deliveries. This pattern of more deliveries of asthma medications, including ICS, between November and May, corresponded to seasonal exacerbations of asthma [ 62 ]. As mentioned above, ICS can also be used to treat other diseases than asthma, such as acute bronchitis or upper-respiratory-tract conditions, that also have a seasonal frequency [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Asthma and COPD: Comparison with International Guidelines and Medication Adherence in Belgium

et al. 2023

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Asthma and chronic obstructive pulmonary disease (COPD) are major chronic conditions. It is possible to limit their impact by controlling symptoms, which limits exacerbations and worsening of the disease, by choosing the appropriate treatment and ensuring that the patient adheres to it. The main purpose of this study was to assess medication adherence and persistence with inhaled medications for chronic treatment of asthma and COPD, as well as to evaluate the factors influencing this adherence. Medication adherence was measured from January 2013 to December 2016 using continuous multiple-interval measures of medication availability (CMA). Persistence was evaluated by treatment episodes (TE). We analyzed the influence of different factors on CMA such as sex, age, type of device, and the realization of the “new medicines service” (NMS), introduced in Belgium in October 2013 to support patients in adhering to their treatment. We also analyzed the consumption of these inhaled medications within the Belgian population and compared them with the Global Initiative for Asthma (GINA) and the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommendations. Medication adherence varied greatly between the different pharmacological classes: inhaled corticosteroids (ICS) alone or in combination with long-acting beta agonists (LABA) had the lowest medication adherence and persistence, while adherence was highest for the long-acting muscarinic antagonists (LAMA) and LABA/LAMA associations. The NMS seemed to have a positive impact on medication adherence, although few patients completed the two guidance interviews offered by the service. In addition, only a minority of the targeted patients took advantage of this new service.

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Section: Discussionmentioning

confidence: 99%

Asthma and COPD: Comparison with International Guidelines and Medication Adherence in Belgium

et al. 2023

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“…9 Among DPI, commonest ICS used was budesonide rotacap and commonest combination was inhaled budesonide and formoterol, this was in concurrence with previous study. 10 The prescription pattern for selection of drug class and route of administration is in accordance with the Global initiative for asthma and Britain thoracic society guidelines.…”

Section: Discussionmentioning

confidence: 99%

Prescription pattern among patients having mild to moderate bronchial asthma using metered dose inhaler and dry powder inhaler in tertiary hospital in western india

Akhoon

Brashier

2018

Int J Basic Clin Pharmacol

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Background: Bronchial asthma is a syndrome characterized by airflow obstruction that manifests as shortness of breath, wheezing and cough. The treatment is tailored according to the severity of the disease. The drugs used for treatment of bronchial asthma include inhaled corticosteroids, beta-2 agonists, methylxanthines, leukotriene antagonists and mast cell stabilizers. Despite the availability of all these drugs, which are recommended for the treatment, not every patient achieves complete control of the disease. The reason behind this could be irrational prescribing of drugs for the treatment and errors in the technique of using inhaler devices. Though rational prescribing of drugs and correct technique for the use of inhaler can be improved by proper training of target population, but there is paucity of such data in our country. Methods: This study was planned to monitor prescription pattern and errors in use of inhalation devices, in patients diagnosed as cases of mild to moderate bronchial asthma, attending Out Patient Department (OPD) of respiratory medicine of a tertiary hospital. A total of 207 patients were recruited and their prescription pattern and inhalation technique were assessed. Results: The study showed that inhaled short acting β2-agonists and inhaled corticosteroids were the most commonly used drug groups, which were prescribed to all the patients in the study, followed by long acting β2-agonists, leukotriene antagonists and methylxanthines in decreasing order. Conclusions: As a conclusion, the treating physicians were prescribing according to the laid down guidelines. It is concluded that such studies should be periodically done to ensure the adherence to the treatment guidelines.

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“…47 Treatment adherence correlates with the periods in which symptoms and asthma exacerbation frequency is highest. 48 Refills for asthma controller prescriptions are highest throughout the winter months, and lower in summer when asthma control is highest. 48 This pattern may contribute to the frequency or severity of severe asthma attacks in the autumn.…”

Section: Causes Of Poor Treatment Adherencementioning

confidence: 99%

“…48 Refills for asthma controller prescriptions are highest throughout the winter months, and lower in summer when asthma control is highest. 48 This pattern may contribute to the frequency or severity of severe asthma attacks in the autumn. Thus, the unique nature of inhaled treatment, the requirement for accurate inhalation technique, coupled with seasonal distribution of asthma symptoms and exacerbations may contribute to a significant portion of poor treatment adherence.…”

Section: Causes Of Poor Treatment Adherencementioning

confidence: 99%

Improving Medication Adherence in Asthma

Kerr

Brennan

Hale

et al. 2022

Semin Respir Crit Care Med

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In little over a generation, the ingenuity of scientists and clinician researchers has developed inhaled medications and pathway-specific biological agents that control the inflammation and physiology of asthma. Unfortunately, whether it is because of cost or difficulty understanding why or how to use inhaled medications, patients often do not take these medications. The consequences of poor treatment adherence, loss of control and exacerbations, are the same as if the condition remained untreated. Furthermore, poor adherence is difficult to detect without direct measurement. Together this means that poor treatment adherence is easily overlooked and, instead of addressing the cause of poor adherence, additional medicines may be prescribed. In other words, poor treatment adherence is a risk for the patient and adds cost to healthcare systems. In this article, we discuss the rationale for and the delivery of successful interventions to improve medication adherence in asthma. We contextualize these interventions by describing the causes of poor treatment adherence and how adherence is assessed. Finally, future perspectives on the design of new interventions are described.

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Seasonal patterns of Asthma medication fills among diverse populations of the United States

Cited by 11 publications

References 21 publications

Asthma and COPD: Comparison with International Guidelines and Medication Adherence in Belgium

Asthma and COPD: Comparison with International Guidelines and Medication Adherence in Belgium

Prescription pattern among patients having mild to moderate bronchial asthma using metered dose inhaler and dry powder inhaler in tertiary hospital in western india

Improving Medication Adherence in Asthma

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