“…Twenty-four time-series studies of mortality, which used two-pollutant and/or multipollutant models for NO 2 , have been published since the 2005 global update of the WHO air quality guidelines (Burnett et al, 2004;Dales et al, 2004;Kan, Jia & Chen, 2004a,b;Zeka & Schwartz, 2004;Simpson et al, 2005a;Díaz, Linares & Tobías, 2006;Samoli et al, 2006;Brook et al, 2007;Qian et al, 2007Qian et al, , 2010Yamazaki et al, 2007;Chen et al, 2008;Hu et al, 2008;Ren Y et al, 2008c;Wong et al, 2008;Breitner et al, 2009;Chen et al, 2010a;López-Villarrubia et al, 2010;Park, Hong & Kim, 2011;Chiusolo et al, 2011;Chen et al, 2012a,b;Faustini et al, 2012;Chen et al, 2013). 4 All of these papers included adjustments for a metric of PM; 17 of the 24 papers reported positive, though not always statistically significant, short-term associations of NO 2 with mortality for a range of diagnoses and age groups, after adjustment for a PM metric.…”