Seasonal Pattern of Acute Myocardial Infarction in the National Registry of Myocardial Infarction

Ornato, Joseph P.; Peberdy, Mary Ann; Chandra, Nisha; Bush, David E.

doi:10.1016/s0735-1097(96)00411-1

Cited by 137 publications

(81 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The fact that onset of STEMI has a circadian rhythm with a peak during diurnal hours has been well described 4, 5, 6, 7, 8, 9, 10, 11, 12. A seasonal pattern13 in the occurrence of STEMI was also found with a salient peak of cases in the winter months and a marked nadir of cases in the summer months 14, 15, 16, 17, 18, 19. Several studies have investigated the reason behind the winter peak and suggested that STEMI is more common in winter and more common on colder days, independent of season 20, 21.…”

Section: Introductionmentioning

confidence: 83%

“Summer Shift”: A Potential Effect of Sunshine on the Time Onset of ST‐Elevation Acute Myocardial Infarction

Cannistraci

Nieminen

Nishi³

et al. 2018

JAHA

View full text Add to dashboard Cite

Background ST‐elevation acute myocardial infarction (STEMI) represents one of the leading causes of death. The time of STEMI onset has a circadian rhythm with a peak during diurnal hours, and the occurrence of STEMI follows a seasonal pattern with a salient peak of cases in the winter months and a marked reduction of cases in the summer months. Scholars investigated the reason behind the winter peak, suggesting that environmental and climatic factors concur in STEMI pathogenesis, but no studies have investigated whether the circadian rhythm is modified with the seasonal pattern, in particular during the summer reduction in STEMI occurrence.Methods and ResultsHere, we provide a multiethnic and multination epidemiological study (from both hemispheres at different latitudes, n=2270 cases) that investigates whether the circadian variation of STEMI onset is altered in the summer season. The main finding is that the difference between numbers of diurnal (6:00 to 18:00) and nocturnal (18:00 to 6:00) STEMI is markedly decreased in the summer season, and this is a prodrome of a complex mechanism according to which the circadian rhythm of STEMI time onset seems season dependent.ConclusionsThe “summer shift” of STEMI to the nocturnal interval is consistent across different populations, and the sunshine duration (a measure related to cloudiness and solar irradiance) underpins this season‐dependent circadian perturbation. Vitamin D, which in our results seems correlated with this summer shift, is also primarily regulated by the sunshine duration, and future studies should investigate their joint role in the mechanisms of STEMI etiogenesis.

show abstract

Section: Introductionmentioning

confidence: 83%

“Summer Shift”: A Potential Effect of Sunshine on the Time Onset of ST‐Elevation Acute Myocardial Infarction

Cannistraci

Nieminen

Nishi³

et al. 2018

JAHA

View full text Add to dashboard Cite

show abstract

“…3- 5 The physiological changes in hemodynamics, 6-8 vascular status and hematological changes, 9-12 as well as environmental factors, contribute to this variation. 2-4, 13 These circadian variations are also associated with the patient's response, medical management and prognosis.…”

mentioning

confidence: 99%

Periodic Variation and Its Effect on Management and Prognosis of Korean Patients With Acute Myocardial Infarction

Park

Koo

Lee

et al. 2010

Circ J

View full text Add to dashboard Cite

Background:The characteristics of the periodic variation in acute myocardial infarction (AMI) and the subsequent effect on management and prognosis have not been fully investigated in a large number of Asian populations. Methods and Results:From a prospective, observational multicenter online registry, 4,573 patients diagnosed as AMI in Korea from January to December 2006 were included. The highest incidence of AMI was between 8 a.m. and noon. The number of cases was highest in the winter and lowest in the autumn (13.6 vs 11.4 patients per day, P<0.001). Patients with symptom onset during working hours had a shorter time to first medical contact (203±288 min) compared with out-of-hours onset (230±288 min, P=0.003). In patients who underwent primary angioplasty, out-of hours symptom onset was associated with a greater time delay in both the patient's and the medical facility's response (door-to-balloon time out-of hours vs working hours: 101±54 min vs 84±44 min, P<0.001). In patients with ST-segment elevation myocardial infarction, symptoms to first medical contact showed a significant relationship to in-hospital mortality (for every 10 min of symptoms to first medical contact, odds ratio 1.006, 95% confidence interval 1.001-1.012, P=0.018) Conclusions: Circadian and periodic variation in AMI exists in Korean patients, which resulted in different patient behavior, hospital management and outcomes. (Circ J 2010; 74: 970 - 976)

show abstract

“…These events explain their high scores on the Holmes' social readjustment rating scale [9] , and can lead to cardiovascular instability such as vasomotor reaction [10] and platelet aggregation [11] resulting in critical events [12][13][14][15] . Although Central Japan can be terribly hot and humid in summer and cold in winter, we could find no seasonal variation in sudden death, as observed in the whole population of this area (our unpublished observation based on the vital statistics) and of some other regions [16][17][18] , in which sudden deaths of the elderly predominated. Thus, the younger generation might be able to withstand the poor climate but still be vulnerable to changes in the psychosocial environment.…”

Section: Discussionmentioning

confidence: 51%

Sudden death in the working population; a collaborative study in Central Japan

Kawamura

Kondo²,

Hirai³

et al. 1999

European Heart Journal

View full text Add to dashboard Cite

Aim Few epidemiological data are available describing the sudden death of persons in their prime. This study aims to elucidate when and how sudden death occurs among employees.Methods A total of 196 775 employees from 10 workplaces in Central Japan were surveyed for non-traumatic sudden death during 1989-1995. Demographic data and information regarding onset were collected by their workplace healthcare professionals. ResultsWe identified 251 male and 13 female cases of sudden death. The annual incidence was 21·9 (for men) and 5·7 (for women) per 100 000 population. Sudden death occurred more frequently in April when the new business year starts (risk ratio [95% confidence interval], 1·62 [0·94-2·79]) than in other months, without seasonality. Sudden death peaked on Sundays (risk ratio, 1·90 [1·20-2·99]) and Saturdays (risk ratio, 1·36 [0·83-2·21]) as compared with weekdays, and was likely to occur in the small hours (risk ratio, 1·71 [0·94-3·10] at 00-0300 h and 1·47 [0·79-2·72] at 0300-0600 h vs at 0900-1200 h. Only 17% of employees died at work, which was significantly less than expected (P<0·001). ConclusionThese findings differed from those of elderly people and suggest that sudden death of persons in their prime is related to occupational stress and its relief. (Eur Heart J 1999; 20: 338-343)

show abstract

Seasonal Pattern of Acute Myocardial Infarction in the National Registry of Myocardial Infarction

Abstract: We conclude that there is a seasonal pattern to the reporting rate of cases of AMI in the NRMI. This observation further supports the hypothesis that acute cardiovascular events may be triggered by events that are external to the atherosclerotic plaque.

Cited by 137 publications

References 37 publications

“Summer Shift”: A Potential Effect of Sunshine on the Time Onset of ST‐Elevation Acute Myocardial Infarction

“Summer Shift”: A Potential Effect of Sunshine on the Time Onset of ST‐Elevation Acute Myocardial Infarction

Periodic Variation and Its Effect on Management and Prognosis of Korean Patients With Acute Myocardial Infarction

Sudden death in the working population; a collaborative study in Central Japan

Contact Info

Product

Resources

About