Seasonal Occurrence of Abdominal Pain and Endoscopic Findings in Patients with Gastric and Duodenal Ulcer Disease

Gibiński, K; Rybicka, J; Nowak, Andrzej; Czarnecka, Karolina

doi:10.3109/00365528209182235

Cited by 21 publications

(5 citation statements)

References 8 publications

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“…The reason why some ulcers are asymptomatic is unknown. In controlled trials, both asymptomatic duodenal ulcers and gastric ulcers have been found in a substantial proportion of cases (44,45). We found that eight subjects (19.5 percent of all ulcer patients and 0.8 percent of the study population) had asymptomatic PUD.…”

Section: Discussionmentioning

confidence: 67%

Peptic Ulcer Disease in a General Adult Population

Aro¹,

Storskrubb²,

Ronkainen³

et al. 2006

American Journal of Epidemiology

158

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The authors' aim in this study was to explore the prevalence, symptomatology, and risk factors for peptic ulcer in a general adult population. Between December 1998 and June 2001, the authors surveyed a random sample (n=3,000) of the adult population (n=21,610) in two communities in northern Sweden using a validated questionnaire, the Abdominal Symptom Questionnaire (response rate=74%). A subsample (n=1,001) of the responders was randomly invited to undergo esophagogastroduodenoscopy and symptom assessment (response rate=73%). The prevalence of peptic ulcer was 4.1% (20 gastric ulcers and 21 duodenal ulcers). Nausea and gastroesophageal reflux were significant predictors of peptic ulcer disease, but epigastric pain/discomfort was not. Six persons with gastric ulcer and two persons with duodenal ulcer were asymptomatic. Eight subjects with duodenal ulcer (38%) lacked evidence of current Helicobacter pylori infection. Five (25%) of the gastric ulcers and four (19%) of the duodenal ulcers were idiopathic (no use of aspirin or nonsteroidal antiinflammatory drugs, no H. pylori infection). Smoking, aspirin use, and obesity were risk factors for gastric ulcer; smoking, low-dose (

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Section: Discussionmentioning

confidence: 67%

Peptic Ulcer Disease in a General Adult Population

Aro¹,

Storskrubb²,

Ronkainen³

et al. 2006

American Journal of Epidemiology

158

View full text Add to dashboard Cite

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“…Although some consider erosive duodenitis to be a separate entity, most consider it to be a variety of duodenal ulcer 19 , . 20 In the intention‐to‐treat analysis, losses during follow‐up, are considered as failures.…”

Section: Discussionmentioning

confidence: 99%

Randomized study comparing omeprazole with ranitidine as anti‐secretory agents combined in quadruple second‐line Helicobacter pylori eradication regimens

Michopoulos

Tsibouris

Bouzakis

et al. 2000

Aliment Pharmacol Ther

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The pathogenic role of Helicobacter pylori in chronic active gastritis and its association with duodenal ulcer disease in 95±99% of patients is well established. 1 Therefore the 1994 National Institute of Health (NIH) consensus development conference recommended the eradication of H. pylori in all patients with documented peptic ulcer disease. 2 The ideal eradication regimen remains elusive; previously used double regimens (omeprazole plus amoxycillin) had a success rate ranging from 30 to 80%. 3 The aim of this study was to compare the ef®cacy of either omeprazole or ranitidine combined in a quadruple regimen including tripotassium dicitrato bismuth, metronidazole and tetracycline hydrocloride as a second-line treatment in patients with erosive duodenitis or duodenal ulcer in whom a non-metronidazole-based anti-H. pylori therapy had previously failed. Currently used eradication regimens show ef®cacy ranging from 80 to 95%. 4 Quadruple therapy comprising a proton pump inhibitor in combination with bismuth triple therapy appears to produce the highest eradication rates

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“…Endoscopy is the most sensitive diagnostic test for peptic ulcers. The main role of endoscopy in patients with uncomplicated Peptic Ulcer disease is to confirm the diagnosis, identify lesions too small to be detected by radiographic examination and to rule out malignancy by performing endoscopic biopsy 7 .…”

Section: Introductionmentioning

confidence: 99%

Clinical Profile and Esophagogastroduodenoscopy Finding in Patients with Acid Peptic Disease at a Tertiary Health Care Centre

Krithika

Mogal

2017

mvpjms

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Background and Aims: Acid Peptic Diseases (APD) is a common disorder. Population based survey revealed that 44% of the population reported monthly heartburn and 19.8% suffered from heartburn or acid regurgitation at least once a week. An approximate prevalence of 10-20 % was identified for GERD, in the Western world while in Asia this was lower, at less than 5% In this study, we are going to study the clinical features and esophagogastroduodenoscopy (EGD) findings in patients presenting in our centre in order to come to a precise diagnosis and indentify various risk factors contributing to it. Methods and Methodology: 80 patients (53 males, mean age 44 years) were evaluated in the present study after they satisfy the inclusion and exclusion criteria. Patients were posted for endoscopy and findings were tabulated. Results: This age distribution among the 80 patients subjected to EDG over a period of 2 years with maximum i.e., 28.75% was in the 41-50 age groups. The most common symptom at presentation was epigastric pain seen in 84% of patients (67 cases), followed by retrosternal burning sensation seen in 51% of patients (41 cases) and acid reflux seen in 49% of patients (39 cases). A few of the risk factors for APD were evaluated, 34% of study group consumed alcohol, 22.5% were smokers and 19% tobacco chewers. In patients who smoked (total 18) EGD findings was suggestive of severe disease in most of them (14 cases) cases had evidence of severe disease. The combination of smoking and alcohol consumption showed more severe form of disease. Most common finding in endoscopy in esophagus was erosions in seen in 19% of patients, gastritis in stomach 22% and duodenitis seen in 2.5% of cases. Prevalence of GERD was 21% and peptic ulcers were was found in 7.5% of study population. Conclusion: APD is more common in males. Smoking, alcohol and NSAIDS usage is associated with more severe form of APD.

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Seasonal Occurrence of Abdominal Pain and Endoscopic Findings in Patients with Gastric and Duodenal Ulcer Disease

Cited by 21 publications

References 8 publications

Peptic Ulcer Disease in a General Adult Population

Peptic Ulcer Disease in a General Adult Population

Randomized study comparing omeprazole with ranitidine as anti‐secretory agents combined in quadruple second‐line Helicobacter pylori eradication regimens

Clinical Profile and Esophagogastroduodenoscopy Finding in Patients with Acid Peptic Disease at a Tertiary Health Care Centre

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