Seasonal humidity may influence Pseudomonas aeruginosa hospital-acquired infection rates

Ramos, Guilherme Piovezani; Rocha, Jaime L.; Tuon, Felipe Francisco

doi:10.1016/j.ijid.2013.03.002

Cited by 47 publications

(31 citation statements)

References 16 publications

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“…Urinary tract infections were associated with higher precipitation (p = 0.04) and temperature (p = 0.02), while hospital-acquired pneumonia was associated with humidity (p = 0.03) and precipitation (p = 0.03). 31 It is unclear why the rate of SSI in our network due to S. aureus increased in the summer but the rate of SSI due to gram-negative rods did not.…”

Section: Discussionmentioning

confidence: 81%

“…For example, infections caused by gram-negative bacteria such as Escherichia coli, Acinetobacter baumanii, Pseudomonas aureginosa , and Enterobacter cloacae occur more frequently in warmer summer and fall months than the remainder of the year. 13,24,29,31,33 Similarly, skin and soft-tissue infections caused by Staphylococcus aureus occur more frequently in the summer, 9,24,36 while pneumonia due to methicillin-resistant S. aureus (MRSA) may occur more frequently in the winter. 16,19,35 …”

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confidence: 99%

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Postoperative infection in spine surgery: does the month matter?

Durkin

Dicks

Baker

et al. 2015

SPI

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OBJECT The relationship between time of year and surgical site infection (SSI) following neurosurgical procedures is poorly understood. Authors of previous reports have demonstrated that rates of SSI following neurosurgical procedures performed during the summer months were higher compared with rates during other seasons. It is unclear, however, if this difference was related to climatological changes or inexperienced medical trainees (the July effect). The aim of this study was to evaluate for seasonal variation of SSI following spine surgery in a network of nonteaching community hospitals. METHODS The authors analyzed 6 years of prospectively collected surveillance data (January 1, 2007, to December 31, 2012) from all laminectomies and spinal fusions from 20 hospitals in the Duke Infection Control Outreach Network of community hospitals. Surgical site infections were defined using National Healthcare Safety Network criteria and identified using standardized methods across study hospitals. Regression models were then constructed using Poisson distribution to evaluate for seasonal trends by month. Each analysis was first performed for all SSIs and then for SSIs caused by specific organisms or classes of organisms. Categorical analysis was performed using two separate definitions of summer: June through September (definition 1), and July through September (definition 2). The prevalence rate of SSIs during the summer was compared with the prevalence rate during the remainder of the year by calculating prevalence rate ratios and 95% confidence intervals. RESULTS The authors identified 642 SSIs following 57,559 neurosurgical procedures (overall prevalence rate = 1.11/100 procedures); 215 occurred following 24,466 laminectomies (prevalence rate = 0.88/100 procedures), and 427 following 33,093 spinal fusions (prevalence rate = 1.29/100 procedures). Common causes of SSI were Staphylococcus aureus (n = 380; 59%), coagulase-negative staphylococci (n = 90; 14%), and Escherichia coli (n = 41; 6.4%). Poisson regression models demonstrated increases in the rates of SSI during each of the summer months for all SSIs and SSIs due to gram-positive cocci, S. aureus, and methicillin-sensitive S. aureus. Categorical analysis confirmed that the rate of SSI during the 4-month summer period was higher than the rate during the remainder of the year, regardless of which definition for summer was used (definition 1, p = 0.008; definition 2, p = 0.003). Similarly, the rates of SSI due to grampositive cocci and S. aureus were higher during the summer months than the remainder of the year regardless of which definition of summer was used. However, the rate of SSI due to gram-negative bacilli was not. CONCLUSIONS The rate of SSI following fusion or spinal laminectomy/laminoplasty was higher during the summer in this network of community hospitals. The increase appears to be related to increases in SSIs caused by gram-positive cocci and, more specifically, S. aureus. Given the nonteaching nature of these hospitals, the findings demonstrate that increases in the rate of SSI during the summer are more likely related to ecological and/or environmental factors than the July effect.

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Section: Discussionmentioning

confidence: 81%

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confidence: 99%

Postoperative infection in spine surgery: does the month matter?

Durkin

Dicks

Baker

et al. 2015

SPI

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“…These results were consistent with (Kaur and Wankhede, 2013). They were found that 65% of the isolates resistant to antibio-tics have the ability to form the biofilm, unlike the isolates that cannot form This biofilm indicates the importance of the biofilm and its role in the emergence of highly antibiotics resistance by many of bacterial species that produce it (Bacalso et al, 2011) that help it to adhere to host cells (Vallet et al, 2004) and gave it the protection of bacteria from external conditions is not appropriate, which helps to stay on hard surfaces, especially in the hospital environment and this leads to the occurrence of injuries acquired from hospitals (Nosocomial infections) (Ramos et al, 2013).…”

Section: Resultsmentioning

confidence: 99%

Detection of Casp-5 Gene as Inflammatory Factor in Iraqi Patients With Pseudomonas Aeruginosa Infections

Alwan¹

2020

Pak J. Biotech

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Pseudomonas aeruginosa is define as one of an aerobic Gram-negative bacteria that considered as one of most problematic nosocomial emerged pathogens. This study was performed on 50 isolates and blood patients. Definitive diagnosis of positive P. aeruginosa isolates based on the characteristic examination, the phenotypic of colonies and microscopic morphology which grown in media also biochemical tests for diagnosis of isolates Fifty isolates identified as Pseudomonas aeruginosa, the percentage of isolates according to clinical sources were 19(38%) from burn, 12 (24%) from urine,3(6%) from ear swabs,10(20%) from sputum and 6(12%) from wounds. The diagnosis was conducted and confirmed by using API20E the result of it is 47(94%). The results showed isolates a different ability to resist antibiotics. Amoxicillin-clavulanic acid, Trimethoprim-sulfamethoxazole and Erythromycin were the effectiveness antibiotic against P. aeruginosa 100%.The ability of biofilm formation as a virulence factor, Micro-titer plate method (MTP) was used, results revealed that (46) isolates (92%) of P. aeruginosa have the ability to form biofilm by MTP method. Genotypic detection was done by conventional PCR for 16SrDNA gene by using specific primer (pa-ss) 50(100%) to detect the virulence gene (Flic gene) which is virulence factor gene in p. aeruginosa responsible for activation of caspase-1enzyme, the result showed 45(90%) positive. all the blood sample the results were positive %100 . Sequencing for 20 casp-5 PCR product to detect variations in gene of Iraqi population and the results showed 20 sample from 20 have a genetic variation, heterozygous nucleotide.

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“…Few studies determined the relationship of increasing temperature and humidity with the nosocomial urinary tract infection caused by Pseudomonas aeruginosa. Some other studies linked urinary tract infections with high temperature and low humidity (17,18,19). The relationship between humidity and urinary tract infection needs to be further investigated before reaching any definite conclusions.…”

Section: Relationship Between Environmental Conditions and Nosocomialmentioning

confidence: 99%

Relationship between Environmental Conditions and Nosocomial Infection Rates in Intensive Care Unit

Şimşek¹,

Grassie²,

Emre³

et al. 2017

Med J Islamic World Acad Sci

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Intensive care units (ICUs) are important departmants at the hospital for nosocomial infections. Although an ICU has 5%-10% of the hospital beds, 25%-50% of the nosocomial infections originate from the ICU (1,2). Both ventilator-related pneumonia (VRP) and catheter-related urinary tract infections (CRUIs) are the most common infections in the ICU (3). Many risk factors are responsible for nosocomial infection in the ICU (1,4). Some of the risk factos are related to the patient, whereas the others are related to the external factors (1,4). It is known that improving the risk factors decreases the infection, mortality, morbidity, and cost (1,3).The environmental conditions affect the infection rate in the ICU (5,6). The patient number in the room, being in single or multiple patient room, space in the room, and design of the room are important for infecton control in the ICU (2,5,6,7,8). Generally efficient airconditioning, filter, heat, and humidity systems are important for infection control at the hospital. These systems are more important than the others in some departments such as the ICU (9). ABSTRACTIntensive care units (ICUs) are the most important departments of a hospital regarding nosocomial infections. Many risk factors contribute to the infection rates in ICUs. These risk factors can be related to the patient or environment. Environmental conditions are important in infection control. Nurse/patient ratio has been shown to be related to nosocomial infection rates. This study aimed to investigate the effects of some of these factors on nosocomial infection rates in ICUs.The effects of changes in environmental conditions, such as area around the patient bed, temperature, humidity, and nurse/ patient rates on nosocomial infection rates were examined retrospectively in the ICU from January 2012 to June 2014 in this study.The total infection rate, ventilator associated pneumonia rate, and catheter-related urinary tract infection rate were found to be 7.67%, 14.53%, and 5.47%, respectively. Despite a statistically significant relationship between all infection rates and the size of the area around the patient bed, no relationship was detected between the nurse/patient rates and the infection rates. Between temperature and humidity, only humidity had a statistically significant relationship with catheterrelated urinary tract infection rates.Nurse/patient ratio is important in ICUs but the other factors related to the quality of the work and infection control are also important. The size of the area around the patient bed has been shown to have an important effect on infection control. This study reported a direct relationship of the size of the area around the patient bed with the infection rates. More studies are needed to evaluate the relationship between temperature and humidity and nosocomial infection rates.

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Seasonal humidity may influence Pseudomonas aeruginosa hospital-acquired infection rates

Abstract: Climatic conditions are another factor that may interfere with the IR of Pseudomonas aeruginosa.

Cited by 47 publications

References 16 publications

Postoperative infection in spine surgery: does the month matter?

Postoperative infection in spine surgery: does the month matter?

Detection of Casp-5 Gene as Inflammatory Factor in Iraqi Patients With Pseudomonas Aeruginosa Infections

Relationship between Environmental Conditions and Nosocomial Infection Rates in Intensive Care Unit

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