Abstract-Along the Sakarya River, samples were taken from 2 different points; the first one was the Cifteler where the source of Sakarya River is located and the second one was Karasu area where Sakarya River ran to the Black Sea. Samples were collected during 2 different seasons; in winter and in summer in order to observe the seasonal effect. Trihalomethanes (THMs) and water quality parameters like Dissolved Organic Carbon (DOC), Ultraviolet Absorbance at 254 nm Wavelength (UV254), hardness, and conductivity values were examined. In order to remove the organic matter and THMs ozone and membrane process were performed. Good treatment efficiency was obtained with ozone and membrane process. The removal efficiencies of THMFP were found to be approximately 70%. Also, all parameters presented higher values in summer compared to winter. It was observed from the FT-IR analysis results that the aromatic and aliphatic functional groups in water changed after the treatment with ozone; and that peak values decreased more after the ozone+membrane treatment. TheSEM analysis showed that some compounds, such as Ca, Mg, and Fe, have been formed on the surface of the membrane after the purification through the membrane only, however these compounds decreased both in weight and size when membrane filtration is performed after a pre-ozonization.