Seasonal changes in serum calcium, PTH and vitamin D levels in patients with primary hyperparathyroidism

Nevo-Shor, Anat; Kogan, Slava; Joshua, Ben‐Zion; Bahat-Dinur, Anat; Novack, Victor; Fraenkel, Merav

doi:10.1016/j.bone.2016.05.012

Cited by 20 publications

(15 citation statements)

References 33 publications

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“…These viruses have become a source of considerable human and animal morbidity and mortality (Cox and Subbarao, ; Peretz et al, ). Other studies have found strong evidence relating human and animal health degradation to the length of the season (Aziz‐Boaron et al, ; Nevo‐Shor et al, ; Fraenkel et al, ). From a healthcare system point of view, predictions of the magnitude and timing of upcoming epidemics could greatly assist in early preparations and developing mitigation strategies (Yaari et al, ).…”

Section: Introductionmentioning

confidence: 98%

The seasons’ length in 21st century CMIP5 projections over the eastern Mediterranean

Hochman

Harpaz

Saaroni

et al. 2018

Intl Journal of Climatology

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The eastern Mediterranean (EM) is expected to be influenced by climate changes that will significantly affect ecosystems, human health and socio‐economic aspects. One aspect of climate change in this vulnerable area is the length of the seasons, especially that of the rainy winter season against the warm and dry summer. Here, the synoptic seasons’ definition of Alpert, Osetinsky, Ziv, and Shafir (2004a) was applied to an ensemble of eight Coupled Model Inter‐Comparison Project phase 5 (CMIP5) models, under RCP8.5 and RCP4.5 scenarios, to predict the changes in the lengths of EM seasons during the 21st century. It is shown that the ensemble adequately represents the annual cycle of the main synoptic systems over the EM. The analysis further suggests that at the end of the 21st century, the duration of the synoptic summer, characterized by the occurrence of the Persian Trough, is expected to be lengthened by 49%, while the synoptic winter, characterized by the occurrence of the Cyprus Low, is expected to be shortened by 56% under the RCP8.5 scenario. This may lead to substantial changes in the hydrological regime and water resources, reduce the potential of dry farming, increase the risk of fires and air pollution and change the timing of seasonal health hazards.

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Section: Introductionmentioning

confidence: 98%

The seasons’ length in 21st century CMIP5 projections over the eastern Mediterranean

Hochman

Harpaz

Saaroni

et al. 2018

Intl Journal of Climatology

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“…It can also be expected that factors affecting vitamin D levels may also affect the disease severity or success of localization studies. Changes in PTH level and disease severity due to seasonal vitamin D variations have been shown in several studies 9–11 . Although there are many studies about the factors affecting the sensitivity of localization studies in the literature, there are few studies with conflicting results, which have investigated the effect of vitamin D level on the success of localization studies.…”

Section: Introductionmentioning

confidence: 85%

Serum Vitamin D Level Does not Affect The Sensitivity of Parathyroid Adenoma Localization Tests

Sencar

Sakiz

Ünsal

et al. 2019

Sci Rep

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The aim of the present study was to evaluate the predictive value of 25-hydroxyvitamin D, calcium and parathormone level, co-existence of thyroid nodule, thyroidectomy history and adenoma volume on the success of neck ultrasound (US) and technetium-99m sestamibi (MIBI) scan in primary hyperparathyroidism (PHP) patients. This study included 256 patients with PHP who underwent parathyroidectomy. 169 (%66) patients had vitamin D deficiency and 56 (%22) of patients had insufficiency. The sensitivity of US and MIBI studies showed no difference between vitamin D deficiency, insufficiency and replete groups (%80.5, %82 and %71 (p > 0.05) and %81, %84 and %71 respectively (p > 0.05)). Vitamin D level was not found to be an independent predictor of localization on either US or MIBI scan after adjusting for different variables (p > 0.05). Calcium level was found to be an independent predictor for US sensitivity (r 2 :0,033, p:0,032) and parathormone level for MIBI sensitivity (r 2 :0,05, p:0,025). The co-existence of nodular thyroid disease and history of thyroidectomy significantly decreased the sensitivity of US (%76 and %43). MIBI sensitivity was not impaired by nodular disease but the history of thyroidectomy also impaired the sensitivity of MIBI (%43). As a result vitamin D level does not affect the sensitivity of preoperative localization tests.

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“…Direct ELISA kit #MBS2601819 (MyBio‐Source, CA) was used to determine vitamin D concentration in rat serum according to the manufacturer's instructions (Almajwal et al, 2019). Serum calcium indicates the efficiency of vitamin D. Serum calcium levels were measured with Backman assay (Nevo‐Shor et al, 2016).…”

Section: Methodsmentioning

confidence: 99%

Bioavailability, rheology, and sensory evaluation of mayonnaise fortified with vitamin D encapsulated in protein‐based carriers

Khan

Butt

Pasha

et al. 2020

Journal of Texture Studies

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Vitamin D lost its functionality during processing and storage, thus, encapsulation with proteins is desirable to preserve bioactivity. The aim of the current study was to develop encapsulated vitamin D fortified mayonnaise (VDFM) using whey protein isolates (WPI) and soy protein isolates (SPI) as encapsulating materials in three different formulations, that is, 10% WPI, 10% SPI, and 5/5% WPI/SPI. Increased shear stress decreased the apparent viscosity along with significant effects on the loss modulus of VDFM. WPI encapsulates showed better results as compared to SPI. WPI based VDFM (M 1) depicted the best results in terms of size and dispersion uniformity of oil droplets. Hue angle and total change differed significantly among treatments. The highest value for overall acceptability was acquired by M 3 (5:5%WPI:SPI-encapsulates) thus proceed for in vivo trials. Serum vitamin D level was significantly higher in the encapsulated VDFM rat group (58.14 ± 6.29 nmol/L) than the control (37.80 ± 4.98 nmol/L). Conclusively, WPI and SPI encapsulates have the potential to improve the stability and bioavailability of vitamin D.

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Seasonal changes in serum calcium, PTH and vitamin D levels in patients with primary hyperparathyroidism

Cited by 20 publications

References 33 publications

The seasons’ length in 21st century CMIP5 projections over the eastern Mediterranean

The seasons’ length in 21st century CMIP5 projections over the eastern Mediterranean

Serum Vitamin D Level Does not Affect The Sensitivity of Parathyroid Adenoma Localization Tests

Bioavailability, rheology, and sensory evaluation of mayonnaise fortified with vitamin D encapsulated in protein‐based carriers

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