Seasonal ambient air pollution correlates strongly with spontaneous abortion in Mongolia

Enkhmaa, Davaasambuu; Warburton, Nicole; Javzandulam, Badrakh; Uyanga, Jadambajav; Khishigsuren, Yarinpil; Lodoysamba, Sereeter; Enkhtur, Shonkuuz; Warburton, David

doi:10.1186/1471-2393-14-146

Cited by 88 publications

(66 citation statements)

References 33 publications

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“…In particular, there is evidence of statistical associations between ambient air pollutants and spontaneous abortions. Enkhmaa et al (2014) correlated fetal deaths with mean monthly levels of various air pollutants by means of regression analysis. They used pollution data from Mongolia and 1,219 medical records of women who had a spontaneous abortion in the same country.…”

Section: Discussionmentioning

confidence: 99%

Exposures to Particulate Matter from the Eruptions of the Puyehue Volcano and Birth Outcomes in Montevideo, Uruguay

Balsa

Caffera

Bloomfield

2016

Environ Health Perspect

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Background:The ashes and dust resulting from the 2011 eruptions of the Puyehue volcano in Chile more than doubled monthly averages of PM10 concentrations in Montevideo, Uruguay. Few studies have taken advantage of natural experiments to assess the relationship between ambient air pollutant concentrations and birth outcomes.Objectives:In this study we explored the effect of particulate matter with diameter of ≤ 10 μm (PM10) on perinatal outcomes in Uruguay, a middle-income country in South America with levels of PM10 that in general do not exceed the recommended thresholds. The analyzed outcomes are preterm birth, term birth weight, and term low birth weight.Methods:We took advantage of the sharp variation in PM10 concentrations due to the Puyehue eruptions to estimate the associations between mother’s exposure to PM10 in each trimester of pregnancy and perinatal outcomes. We use birth registries for 2010–2013 and control for covariates, including maternal and pregnancy characteristics, weather, co-pollutants, and calendar quarter and hospital indicators.Results:A 10-μg/m3 increase in exposure to PM10 during the third trimester was associated with a higher likelihood of a preterm birth [odds ratio (OR) = 1.10; 95% CI: 1.03, 1.19]. The association was robust to different model specifications, and increased with categorical exposure levels (OR for third-trimester PM10 ≥ 70 vs. < 30 μg/m3 = 5.24; 95% CI: 3.40, 8.08). Exposures were not consistently associated with birth weight or low birth weight among term births, though second-trimester exposures were associated with higher birth weight, contrary to expectations.Conclusions:Taking advantage of a natural experiment, we found evidence that exposure to high levels of PM10 during the third trimester of pregnancy may have increased preterm births among women in Montevideo, Uruguay.Citation:Balsa AI, Caffera M, Bloomfield J. 2016. Exposures to particulate matter from the eruptions of the Puyehue Volcano and birth outcomes in Montevideo, Uruguay. Environ Health Perspect 124:1816–1822; http://dx.doi.org/10.1289/EHP235

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Section: Discussionmentioning

confidence: 99%

Exposures to Particulate Matter from the Eruptions of the Puyehue Volcano and Birth Outcomes in Montevideo, Uruguay

Balsa

Caffera

Bloomfield

2016

Environ Health Perspect

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“…A Mongolian study found a dose-dependent relationship between the monthly average SO 2 , NO 2 , CO, PM 10 , and PM 2.5 levels during pregnancy and risk of spontaneous abortions. 53 A few studies have shown or suggested that semen or sperm quality is decreased in areas of high pollution. 54,55…”

Section: Fertilitymentioning

confidence: 99%

Air Pollution and Noncommunicable Diseases

Schraufnagel

Balmes

Cowl

et al. 2019

Chest

391

156

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Air pollution poses a great environmental risk to health. Outdoor fine particulate matter (particulate matter with an aerodynamic diameter < 2.5 mm) exposure is the fifth leading risk factor for death in the world, accounting for 4.2 million deaths and > 103 million disability-adjusted life years lost according to the Global Burden of Disease Report. The World Health Organization attributes 3.8 million additional deaths to indoor air pollution. Air pollution can harm acutely, usually manifested by respiratory or cardiac symptoms, as well as chronically, potentially affecting every organ in the body. It can cause, complicate, or exacerbate many adverse health conditions. Tissue damage may result directly from pollutant toxicity because fine and ultrafine particles can gain access to organs, or indirectly through systemic inflammatory processes. Susceptibility is partly under genetic and epigenetic regulation. Although air pollution affects people of all regions, ages, and social groups, it is likely to cause greater illness in those with heavy exposure and greater susceptibility. Persons are more vulnerable to air pollution if they have other illnesses or less social support. Harmful effects occur on a continuum of dosage and even at levels below air quality standards previously considered to be safe.

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“…Evidence has shown that the inhalation of SO 2 through the nose can lead to the formation of sulfate, which can be absorbed into the lining of the airways and initiate a cascade of inflammation [17]. The regression of levels of ambient pollutants against fetal death as a dose-response toxicity curve revealed very strong dose-dependent response correlations for SO 2 , with r > 0.9 (p < 0.001), in Ulaanbaatar, Mongolia [18]. Although the urinary levels of 1-hydroxypyrene (1-OHP) of Mongolian children have been shown to be associated with polycyclic aromatic hydrocarbons (PAH) co-pollutants, SO 2 and NO 2 were significantly elevated during the cold season and for those living in ger areas or block brick houses in Ulaanbaatar [19].…”

Section: Introductionmentioning

confidence: 99%

Origin and Background Estimation of Sulfur Dioxide in Ulaanbaatar, 2017

Prikaz

Fang

Dash³

et al. 2018

Environments

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Particulate matter studies have been conducted regularly in the capital city of Mongolia. In contrast, studies related to the source and general estimation of levels of sulfur dioxide (SO 2 ) over whole years are lacking. To explore the yearly trend in SO 2 , whole-year data of air pollutants were obtained from the Air Pollution Reducing Department. The results showed that the annual average concentration of SO 2 was 32.43 µg/m 3 at the Amgalan official monitoring station in 2017, which changed from 53 µg/m 3 in 2016, representing a reduction of around 40%. The back-trajectory model and the National Oceanic and Atmospheric Administration (NOAA)'s hybrid single particle Lagrangian integrated trajectory model (HYPSLIT) were used to determine the source of SO 2 . A total of 8760 backward trajectories were divided into eight groups. The results showed that 78.8% of the total trajectories in Ulaanbaatar came from an area inside Mongolia. The results showed that pollutants enter Ulaanbaatar mainly from the northwest and north during the winter season. There are industrial cities, such as Darkhan and Sukhbaatar, in North Mongolia. Air pollutants created in the industrial area traveled into Ulaanbaatar during the winter season.

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Seasonal ambient air pollution correlates strongly with spontaneous abortion in Mongolia

Cited by 88 publications

References 33 publications

Exposures to Particulate Matter from the Eruptions of the Puyehue Volcano and Birth Outcomes in Montevideo, Uruguay

Exposures to Particulate Matter from the Eruptions of the Puyehue Volcano and Birth Outcomes in Montevideo, Uruguay

Air Pollution and Noncommunicable Diseases

Origin and Background Estimation of Sulfur Dioxide in Ulaanbaatar, 2017

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