“…The capability of 1,2,4-triazine derivatives to play the role of «universal base», capable of forming strong complexes with canonic Thy, Ade, Cyt, Gua, prompted us to perform triazine-based synthesis of the hybrid compounds with phenazine-1-carboxylic acid (PCA-1; 2) -non-nucleoside inhibitors [14]. At the same time, taking into account pharmacophoric properties of carboxamide group, we developed convenient methods of obtaining the series of N-substituted amides of triazinyl-6-propanecarboxylic acid (PCA; 3) [15,16] and N-arylamides of PCA-1 (4) [17].…”