Sealapex Xpress and RealSeal XT Feature Tissue Compatibility In Vivo

Silva, Léa Assed Bezerra; Barnett, Frederic; Pumarola-Suñé, José; Cañadas, Piedad S.; Filho, Paulo Nelson; Silva, Léa Assed Bezerra da

doi:10.1016/j.joen.2014.01.040

Cited by 16 publications

(18 citation statements)

References 32 publications

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“…Human periodontal ligament stem cells were used for this study because periodontal tissues are involved in biological apical sealing (Silva et al . ). Moreover, h PDLSCs have important advantages such as being easily obtained from human teeth, are able to self‐renew and differentiate into many cell types (Ding et al .…”

Section: Discussionmentioning

confidence: 97%

“…This study evaluated three commercially available materials, BR, ES and NCS, which were tested to evaluate their cytocompatibility on hPDLSCs. Human periodontal ligament stem cells were used for this study because periodontal tissues are involved in biological apical sealing (Silva et al 2014). Moreover, hPDLSCs have important advantages such as being easily obtained from human teeth, are able to selfrenew and differentiate into many cell types (Ding et al 2015, Liu et al 2015.…”

Section: Discussionmentioning

confidence: 99%

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Biocompatibility of three new calcium silicate‐based endodontic sealers on human periodontal ligament stem cells

et al. 2016

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Biocompatibility of three new calcium silicate‐based endodontic sealers on human periodontal ligament stem cells

et al. 2016

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“…While the in vitro , in vivo and selected outcome results for this material were generally positive compared to traditional techniques many practitioners complained about its clinical performance. Methacrylate sealer demonstrates the same shortcomings of the traditional sealers (shrinkage and wash out) and is also extremely technique sensitive.…”

Section: Attempts To Improve Root Canal Fillingsmentioning

confidence: 98%

Root filling materials and techniques: bioceramics a new hope?

Trope¹,

Bunes²,

Debelian³

2015

Endodontic Topics

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Instrumentation creates space for canal irrigation, disinfection and root filling. All of these have an impact on the method and size of instrumentation, depending on the philosophy of the dentist and the limitations and requirements set by the equipment used in each phase, especially in root filling. Optimal root filling has many requirements which have been difficult if not impossible to fulfill. Gutta‐percha has been and still is the core material of choice in root fillings, but it requires the use of a sealer in order to obtain better short term and long term seal. However, numerous studies on leakage after root filling have suggested that complete, permanent sealing of the canal against leakage from the oral cavity is usually not obtained. This review takes a critical look at presently available methods for canal instrumentation and filling, and challenges these as far less than optimal with regard to ease of operation, time and technical skills required, weakening of the root/tooth structure and quality of the seal. The authors discuss the above factors from the point of view of bioceramic materials in root filling. Is there a hope of a better future in root filling?

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“…Besides presenting adequate physical properties, satisfactory biological behavior is a necessary requirement for their clinical application. These materials are often in direct contact with apical and periapical tissues and should allow, or even stimulate, the deposition of cementum, leading to biological seal and healing process (3).…”

Section: Introductionmentioning

confidence: 99%

Biological Tissue Response to a New Formulation of a Silicone Based Endodontic Sealer

et al. 2016

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Satisfactory biological behavior is a necessary requirement for clinical application of endodontic materials. In this study, the connective tissue responses to silicone (GuttaFlow 2), epoxy resin (AH Plus) and zinc oxide and eugenol (Endofill) based sealers were compared. Twelve Wistar rats had polyethylene tubes (four per animal) containing one of the tested sealers and empty tubes (negative control) implanted in their subcutaneous tissue. The tubes were randomly placed 2 cm from the spine and at least 2 cm apart from one another. Tissue samples with implants were processed for histological analysis after 7 or 60 days (n=6 animals per period). Inflammatory cells, fibrous condensation and abscess were scored according to their intensity. Friedman, followed by Dunn's post hoc, was used to compare sealers. Differences between the two experimental periods were verified using Mann-Witney U test (p<0.05). At 7 days, most of the histological parameters showed no significant differences amongst groups. Endofill group scored higher than the others for giant cells (o<0.05) and promoted a greater number of samples presenting abscess formation. GuttaFlow 2 tended to show a less intense inflammatory infiltrate compared to the other materials. At 60 days, there were no significant differences between groups in most of the histological parameters evaluated. However, it was observed that Endofill scored higher for macrophages (p<0.05) compared to the control group, and GuttaFlow 2 tended to present lower scores than the others for neutrophils and abscess. GuttaFlow 2 showed proper biological behavior and should be considered adequate for clinical practice.

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Sealapex Xpress and RealSeal XT Feature Tissue Compatibility In Vivo

Cited by 16 publications

References 32 publications

Biocompatibility of three new calcium silicate‐based endodontic sealers on human periodontal ligament stem cells

Biocompatibility of three new calcium silicate‐based endodontic sealers on human periodontal ligament stem cells

Root filling materials and techniques: bioceramics a new hope?

Biological Tissue Response to a New Formulation of a Silicone Based Endodontic Sealer

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