Abstract:Here, we report on the design and function of a membrane nanopore through a DNA origami
square tube with a cross-section of 100 nm2
. When the nanopore is added onto the giant
vesicle membrane, the permeation of hydrophilic fluorescent molecules was observed. It can
be sealed by the existence of the four specific single strand DNAs. A controllable artificial
nanopore should help to communicate the vesicle components with their environment
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