SDD for the Prevention and Control of Outbreaks

Spoel, H. I. van der; Gerritsen, Rik

doi:10.1007/978-88-470-0653-9_11

Cited by 1 publication

(1 citation statement)

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“…This included from September 2002, the use of a ‘short stay’ four-bedded unit outside the ICU area for patients expected to be admitted to the ICU for fewer than 72 h. Secondly, from October 2002 onwards, patients admitted to the ICU received selective decontamination of the digestive tract (SDD). The aim of the SDD treatment in this setting was to reduce colonization of the digestive tract with resistant bacteria [ 18 ]. SDD was given as topical mixture of nonabsorbable antibiotics including tobramycin, colistin and Amphotericin B (respective doses: 80, 100, and 500 mg), applied on the buccal mucosa and as a suspension administered via a nasogastric tube in the gastrointestinal tract, four times a day [ 19 ].…”

Section: Methodsmentioning

confidence: 99%

Impact of single room design on the spread of multi-drug resistant bacteria in an intensive care unit

Halaby¹,

Naiemi

Beishuizen

et al. 2017

Antimicrob Resist Infect Control

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BackgroundCross-transmission of nosocomial pathogens occurs frequently in intensive care units (ICU). The aim of this study was to investigate whether the introduction of a single room policy resulted in a decrease in transmission of multidrug-resistant (MDR) bacteria in an ICU.MethodsWe performed a retrospective study covering two periods: between January 2002 and April 2009 (old-ICU) and between May 2009 and March 2013 (new-ICU, single-room). These periods were compared with respect to the occurrence of representative MDR Gram-negative bacteria. Routine microbiological screening, was performed on all patients on admission to the ICU and then twice a week. Multi-drug resistance was defined according to a national guideline. The first isolates per patient that met the MDR-criteria, detected during the ICU admission were included in the analysis. To investigate the clonality, isolates were genotyped by DiversiLab (bioMérieux, France) or Amplified Fragment Length Polymorphism (AFLP). To guarantee the comparability of the two periods, the ‘before’ and ‘after’ periods were chosen such that they were approximately identical with respect to the following factors: number of admissions, number of beds, bed occupancy rate, per year and month.ResultsDespite infection prevention efforts, high prevalence of MRD bacteria continue to occur in the original facility. A marked and sustained decrease in the prevalence of MDR-GN bacteria was observed after the migration to the new ICU, while there appear to be no significant changes in the other variables including bed occupancy and numbers of patient admissions.ConclusionSingle room ICU design contributes significantly to the reduction of cross transmission of MRD-bacteria.

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Section: Methodsmentioning

confidence: 99%