Scutellin A, a New Neoclerodane Diterpenoid from &lt;I&gt;Scutellaria barbata&lt;/I&gt; (Labiatae)

Zhu, Feng; LIU, Ling-Li; Di, Ying‐Tong; Hao, Xiao‐Jiang; He, Hong‐Ping

doi:10.3724/sp.j.1143.2009.09114

Cited by 4 publications

(2 citation statements)

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“…195,321 Scupontins C, D, and F ( 839–841 ) from S. pontica possess unusual [(3′ S ,3″ S )-3′-[(3″-acetoxybutyryl) oxy]butyryloxy and [(3′ S ,3″ S ,3‴ S )-3′-[[3‴-[(3‴-hydroxybutyryl) oxy]butyryl]oxy]butyryl]oxy substituents, respectively, attached to the C-19 position of the neo -clerodane nucleus. 322 Scutalpin M ( 842 ) also from S. alpine is the first 14-oxidized hexahydrofuro-furan- neo -clerodane derivative isolated from natural sources.…”

Section: Structure Classifications and Sources Of Clerodane Diterpmentioning

confidence: 99%

Clerodane diterpenes: sources, structures, and biological activities

2016

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The clerodane diterpenoids are a widespread class of secondary metabolites and have been found in several hundreds of plant species from various families and in organisms from other taxonomic groups. These substances have attracted interest in recent years due to their notable biological activities, particularly insect antifeedant properties. In addition, the major active clerodanes of Salvia divinorum can be used as novel opioid receptor probes, allowing greater insight into opioid receptor-mediated phenomena, as well as opening additional areas for chemical investigation. This article provides extensive coverage of naturally occurring clerodane diterpenes discovered from 1990 until 2015, and follows up on the 1992 review by Merritt and Ley in this same journal. The distribution, chemotaxonomic significance, chemical structures, and biological activities of clerodane diterpenes are summarized. In the cases where sufficient information is available, structure activity relationship (SAR) correlations and mode of action of active clerodanes have been presented.

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Section: Structure Classifications and Sources Of Clerodane Diterpmentioning

confidence: 99%

Clerodane diterpenes: sources, structures, and biological activities

2016

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“…Mushroom, Agrocybe salicacola Zhu L. Yang, M. Zang, and X.X. Liu [2], is an edible basidiomycete belonging to the order Agaricales. The genus Agrocybe is reported to contain several bioactive metabolites, such as ceramide with inhibitory activity against COX-1,2 [1], indole alkaloids with free radical scavenging ability [3], agrocybin, a peptide with anti-fungal activity [4], polysaccharides with hypoglycemic activity [5], a lectin with mitogenic activity [6], and antiproliferative and differentiating effects [7].…”

Section: Introductionmentioning

confidence: 99%