Scrub Typhus in Children

Zainab, Madiha; Gupta, Atul; Guha, Suparna

doi:10.3126/jnps.v38i1.18659

Cited by 2 publications

(7 citation statements)

References 7 publications

(13 reference statements)

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“…Scrub typhus patients presented with various spectrum of signs and symptoms. Fever was the most common symptom in our study that was similar to other study findings (1,11,12).…”

Section: Discussionsupporting

confidence: 92%

“…Similar seasonal variation has been reported by other authors (6,7,8). The majority of the cases were reported by Zainab et al, and Naveen et al, between June and November (1,9). In another study, maximum number of cases was observed between the month of May and August (10).…”

Section: Discussionsupporting

confidence: 85%

“…Most of the studies showed male preponderance. However, Zainab et al, reported female predominance in their study (1).…”

Section: Discussionmentioning

confidence: 72%

“…In our study eschar was found in only 2.91% cases. In a study conducted by (15,1). Eschar was not found even in a single patient in some previous observational study (13).…”

Section: Discussionmentioning

confidence: 83%

“…In a study conducted by Kishore et al, rash was reported in 14.63% cases (4). In another study conducted by Zainab et al, rash was found in 30% children (1). In other study by Digra et al, rash was found in all children (100%, n=21) ( 16), whereas other authors reported neither eschar nor rash (17).…”

mentioning

confidence: 94%

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A study of scrub typhus in a medical college hospital in West Bengal, India

Mondal¹,

Sarkar²,

Rahaman³

et al. 2022

Biomedicine

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Introduction and Aim: Scrub typhus is one of the leading causes of acute unexplained fever in children. The objective of this study was to determine the serological evidence of scrub typhus and associated clinical features in febrile children. Materials and Methods: This retrospective observational study was performed for a duration of 21 months. Children aged below 12 years, admitted with unexplained fever and other clinical features suggestive of scrub typhus and tested for IgM against scrub typhus were included in our study. A detailed history, clinical profile and sero-prevalence of the children were analysed from record files. Results: Four hundred and seventy one clinically suspected patients of below 12 years were tested for scrub typhus. Out of 471, 172 children were scrub typhus positive. Maximum number of positive cases were detected between the month of August and November. Fever was present in all patients. Nausea and vomiting, abdominal pain, cough, hepatomegaly, splenomegaly, lymphadenopathy, rash, convulsion and jaundice were other presenting clinical features. Eschar was observed only in 2.91% cases. Conclusion: Scrub typhus is to be suspected in every children present with unexplained fever. Early diagnosis and early initiation of specific therapy is crucial for favourable outcome.

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“…Scrub typhus patients presented with various spectrum of signs and symptoms. Fever was the most common symptom in our study that was similar to other study findings (1,11,12).…”

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 85%

“…Most of the studies showed male preponderance. However, Zainab et al, reported female predominance in their study (1).…”

Section: Discussionmentioning

confidence: 72%

“…In our study eschar was found in only 2.91% cases. In a study conducted by (15,1). Eschar was not found even in a single patient in some previous observational study (13).…”

Section: Discussionmentioning

confidence: 83%

mentioning

confidence: 94%

See 3 more Smart Citations

A study of scrub typhus in a medical college hospital in West Bengal, India

Mondal¹,

Sarkar²,

Rahaman³

et al. 2022

Biomedicine

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show abstract

Clinico-demographic and hepatic profile as outcome predictor in scrub typhus in pediatric age group

et al. 2023

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Background: Scrub Typhus, a Rickettsial disease is an emerging tropical disease mainly in South East Asia. Very few studies are there in pediatric age group and mainly limited to epidemiological and clinical profile only. Aims and Objectives: The main objective of this study is to assess different clinical, laboratory, and biochemical parameters denoting hepatic function in scrub typhus and their role in measuring final outcome and disease severity. Materials and Methods: This observational study included 90 children with history of febrile illness for ≥5 days between 1 and 12 years of age, diagnosed to be a case of scrub typhus by positive IgM ELISA test to assess the hepatic involvement by different clinical, laboratory, and radiological parameters and also to find out their role in disease severity and outcome. Results: Fever followed by vomiting was the most common symptoms with eschar evident in only three patients. Raised aspartate transaminase (AST) and alanine transaminase (ALT) were seen in 71.1% and 64.4%, respectively, with hypoalbuminemia in 78.9%, hepatomegaly in 47.8%, and only 2.2% had altered hepatic echotexture on ultrasonography. All of them had ALT: lactate dehydrogenase (LDH) ratio of <5. Shock was the most important predictor of duration of hospital stay whereas serum AST was an important predictor for final outcome and duration of hospital stay. Conclusion: Predominant feature of hepatic involvement in scrub typhus resembles that of anicteric hepatitis. Serum ALT: LDH ratio may be an important indicator of scrub hepatitis. Among lab parameters serum AST is the most important predictor of disease mortality and morbidity.

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Scrub Typhus in Children

Cited by 2 publications

References 7 publications

A study of scrub typhus in a medical college hospital in West Bengal, India

A study of scrub typhus in a medical college hospital in West Bengal, India

Clinico-demographic and hepatic profile as outcome predictor in scrub typhus in pediatric age group

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