Scrotal leiomyoma

Rare case of a scrotal leiomyoma-a diagnostic dilemma: A case report

“…Soft tissue tumors can be either superficial or deep [ 2 ]. There are three types of superficial leiomyomas in the skin and subcutaneous tissue: Piloleiomyomas (erector pilli), angioleiomyomas (blood vessels), and genital leiomyomas, which develop from the smooth muscles of the nipple, vulva, and scrotum [ 3 , 4 ].…”

“…However, in a review by Newman and Fletcher, the presence of any mitotic activity was suggested as a criterion of potential malignancy. Therefore, pathologists should carefully examine these features [ 4 ]. Smooth muscle tumors have an additional feature of showing cytoplasmic positivity for smooth muscle actin (SMA) and desmin, and they test negative for S100 (soluble in 100 % saturated ammonium sulfate solution).…”