Scrotal Kaposi's Sarcoma in HIV-negative patient: A case report and review of the literature

Abstract

Kaposi's Sarcoma (KS) is a malignancy that generally effects the skin, and can be systemic with internal organ involvement. It originates from the vascular endothelium. KS's relationship with human immunodeficiency virus (HIV) infection is well known. Isolated scrotal KS in the urogenital system is quite rare and scrotal KS in an HIV-negative patient is limited to a few cases. In this case report, the biopsy result from the violescent nodular lesions on the scrotum of the HIV-negative 81-year-old patient was found compatible with KS and a pathology was not detected in the systemic screening. With a diagnosis of isolated scrotal KS, the patient underwent surgical excision aimed at the lesions on the scrotum. KS is rare in HIV-negative patients and it is associated with human herpes virus-8 infection.

Imaging of Kaposi sarcoma

“…Imaging studies are rarely needed for evaluation, but can show high T2-signal (Fig. 7), enhancing lesions on MR. KS affecting the scrotum is also extremely rare and very few cases have been recorded [47]; this can include skin involvement and complication such as hydroceles or fluid within the scrotum (Fig. 4).…”

Methionine by soybean and spiruline and bivalent Iron, Calcium and Manganese as catalysts to alleviate skin rashes and fever in monkeypox: A Case report

“…Asymptomatic stomach involvement has been estimated at 82% in classic KS. Therefore, studies have recommended screening patients with KS by endoscopy [4,5]. The value of this screening has not yet been studied in patients with localized KS, as in our case.…”

“…The classical form is often seen in older male patients of Mediterranean or Ashkenazi descent, more commonly affecting the lower extremities and feet. It may rarely show visceral involvement [4,5].…”

“…Kaposi's sarcoma (KS) is not an uncommon vascular tumor [1][2][3][4][5][6][7][8][9][10][11]. It was first described by Moritz Kaposi in 1872.…”

“…It is mainly encountered in patients with HIV. KS affects the skin in a diffuse pattern [1][2][3][4][5][6][7][8][9][10][11]. Isolated scrotal involvement in an immunocompetent patient is a rare presentation.…”