Scrophulariaceae

Amelioration of adriamycin-induced cardiotoxicity bySalsola kaliaqueous extract is mediated by lowering oxidative stress

“…29 Furthermore, two isochinolin alkaloids: salsoline and salsolidine, were found to represent a small composition of the herb (about 0.2%). 30 Also, some antioxidant fatty acids like linolenic, arachidonic, palmitic and stearic acids have been identified together with 4-desmethylsterols derivatives. 31,32 All these promising antioxidant data reported for S. kali and the abundance of S. kali in our area, and since ADR-induced cardiotoxicity is linked to oxidative stress, we have investigated the possible effect of S. kali aqueous extract against ADR-induced cardiotoxicity and also the changes in oxidant-antioxidant status of an experimental mice model.…”