Both the support force inequality on both ends of the roll and the camber are common drawbacks, those were caused by the static indeterminacy of structure design, backlash and offset setting selection on the plate rolling mill. There are many technical literatures for analysing the reasons for generating of the strip camber, which are mainly the external factor analysis, however, the internal cause of the mill roll system is ignored. The negative effects of offset distance setting and side clearances of about 1 mm between the chocks and side surface of the housing window should be considered on the plate rolling mill. In reality, the primary cause of this deviation and the strip camber lies in the interaction between offset distance setting and cross of the rolls. The greater the offset setting value of the plate rolling mill, the greater the generation probability of pressure difference and the camber. Some measures, involving eliminating offset distance setting, effectively controlling the side clearances between chocks and housing window, eliminating initial cross and dynamic cross phenomenon, should be taken to maintain the rolls parallel and to prevent radically the support force inequality on both ends of the roll and strip camber.