Screening Scale Predicts Patients Successfully Receiving Long-term Implantable Left Ventricular Assist Devices

Öz, Mehmet C.; Goldstein, Daniel J.; Pepino, Paolo; Weinberg, Alan; Thompson, Seth; Catanese, Katharine A.; Vargo, Rita L.; McCarthy, Patrick M.; Rose, Eric A.; Levin, Howard R.

doi:10.1161/01.cir.92.9.169

Cited by 151 publications

(85 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Despite the fact that VAD is a good support bridge to HTx, it is still impossible to implant VADs for all patients with heart failure or who are on ECMO. Good outcomes of VAD-supported patients depend on proper selection (13,(16)(17)(18)(19). Oz et al (13) suggested a useful RFSS for the selection of appropriate patients to receive VAD.…”

Section: Discussionmentioning

confidence: 99%

“…Good outcomes of VAD-supported patients depend on proper selection (13,(16)(17)(18)(19). Oz et al (13) suggested a useful RFSS for the selection of appropriate patients to receive VAD. That model provides a useful reference for patient selection and outcome prediction for VAD patients.…”

Section: Discussionmentioning

confidence: 99%

“…For the factor of lung dysfunction, four cases with this risk factor were clustered in the "poor" outcome group, while no patient with this risk factor was in the "favorable" out- On the basis of these analyses, we attempted to develop an RFSS, similar to the proposed RFSS for VAD (13), to predict the outcome for ECMO patients by summating appropriate weight for each significant risk factor. The weights (W) assigned to each of the significant factors were based on their respective coefficients (b) from the multivariate logistic regression model.…”

Section: Development Of Rfss Definition Of End Organ Dysfunctionmentioning

confidence: 99%

“…A receiver-operator characteristic (ROC) curve (Figure 3) was created to test the sensitivity and specificity of the developed RFSS (13,14). The area under curve (AUC) was 0.81, indicating good predictive power of the RFSS.…”

Section: Development Of Rfss Definition Of End Organ Dysfunctionmentioning

confidence: 99%

See 3 more Smart Citations

Risk Factor Screening Scale to Optimize Treatment for Potential Heart Transplant Candidates under Extracorporeal Membrane Oxygenation

Chen

Chi

et al. 2004

American Journal of Transplantation

View full text Add to dashboard Cite

We developed a risk factor-scaling score (RFSS) to select which patients supported by extracorporeal membrane oxygenation (ECMO) were suitable for ventricular assist device (VAD) implantation or heart transplantation (HTx). A total of 78 patients supported with ECMO for more than 48 h due to cardiac origin were included in this study. Patients were categorized into two groups based on the outcomes: the poor outcome group (n = 33) consisted of for those who later died or were later excluded from VAD or HTx; the favorable outcome group (n = 45) consisted of those who were weaned off ECMO finally and survived or were deemed suitable candidates for VAD or HTx. Seven risk factors were significant according to univariate analyses. Based on the regression coefficients of multivariate analysis, the RFSS was developed: (lung dysfunction × 7) + (systemic infection × 3) + (peak lactate > 3 mmole/L × 3) + (kidney dysfunction × 2) + (creatine kinase > 10 000 U/L × 1). Patients with an RFSS of 7 or more were be allocated to the poor outcome group. The RFSS was validated by another group of 30 patients with good correlation. The RFSS provides a way to predict which ECMO-supported patients are suitable candidates for VAD implantation or HTx.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Development Of Rfss Definition Of End Organ Dysfunctionmentioning

confidence: 99%

Section: Development Of Rfss Definition Of End Organ Dysfunctionmentioning

confidence: 99%

See 2 more Smart Citations

Risk Factor Screening Scale to Optimize Treatment for Potential Heart Transplant Candidates under Extracorporeal Membrane Oxygenation

Chen

Chi

et al. 2004

American Journal of Transplantation

View full text Add to dashboard Cite

show abstract

“…Before VAD implantation, patients must be screened for emotional and psychological readiness, family and social support, and home safety. 10,12,38 Family members or friends should be aware that the demands on them will be great; although the longterm demands of care providers decrease with time after heart transplantation, this is not the case with VADs.…”

Section: Social Services and Psychiatric Conditionsmentioning

confidence: 99%