Screening protocol for identifying inorganic oxides with anti-oxidant and pro-oxidant activity for biomedical, environmental and food preservation applications

Mellaerts, Randy; Delvaux, J; Lévêque, Philippe; Wuyts, Benjamin; Mooter, Guy Van den; Augustijns, Patrick; Gallez, Bernard; Hermans, Ive; Martens, Johan A.

doi:10.1039/c2ra20921g

Cited by 4 publications

(4 citation statements)

References 28 publications

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“…It was found that TS-1 zeolite (Ti-containing MFI type zeolite) exhibits comparable or even better anti-oxidant activity in comparison to cerium oxide, while pro-oxidant activity was demonstrated for several other zeolites. 178 A clear finding was that the toxicity of zeolites is dependent on the cell types used in the study. This implies that in vitro studies have to be carried out carefully using representative methodology.…”

Section: Nanosized Zeolitesmentioning

confidence: 99%

“…174 The zeolites with and without functionalization showed different cytotoxicity; the zeolites modified with amine were the most toxic. 178 Further toxicity study of nanosized zeolites in different biological systems is needed. When considering potential applications of biocompatible materials, their interaction with free radicals needs to be considered at an early exploratory stage.…”

Section: Nanosized Zeolitesmentioning

confidence: 99%

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Nanosized microporous crystals: emerging applications

2015

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This review highlights recent developments in the synthesis and unconventional applications of nanosized microporous crystals including framework (zeolites) and layered (clays) type materials. Owing to their microporous nature nanosized zeolites and clays exhibit novel properties, different from those of bulk materials. The factors controlling the formation of nanosized microporous crystals are first revised. The most promising approaches from the viewpoint of large-scale production of nanosized zeolites and clays are discussed in depth. The preparation and advanced applications of nanosized zeolites and clays in free (suspension and powder forms) and fixed (films) forms are summarized. Further the review emphasises the non-conventional applications of new porous materials. A comprehensive analysis of the emerging applications of microporous nanosized crystals in the field of semiconductor industry, optical materials, chemical sensors, medicine, cosmetics, and food industry is presented. Finally, the future needs and perspectives of nanosized microporous materials (zeolites and clays) are addressed.

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Section: Nanosized Zeolitesmentioning

confidence: 99%

Section: Nanosized Zeolitesmentioning

confidence: 99%

Nanosized microporous crystals: emerging applications

2015

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“…Also, it was concluded that the cytotoxicity of zeolites depended on type of the cell line utilized in the research emphasizing that in vitro investigations must employ representative methodologies to achieve reliable data. 37 In our previous research, we investigated the toxicity of both LTL and EMT types of zeolites, categorized in the common class of molecular sieves, against HeLa cells. The HeLa cell interaction with both types of zeolite NPs was assessed by cell viability, reactive oxygen species (ROS), and cell cycle assays.…”

Section: Biosafety and Cytotoxicitymentioning

confidence: 99%

<p>Biomedical Applications of Zeolitic Nanoparticles, with an Emphasis on Medical Interventions</p>

Derakhshankhah¹,

Jafari²,

Sarvari³

et al. 2020

IJN

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The advent of porous materials, in particular zeolitic nanoparticles, has opened up unprecedented putative research avenues in nanomedicine. Zeolites with intracrystal mesopores are low framework density aluminosilicates possessing a regular porous structure along with intricate channels. Their unique physiochemical as well as physiological parameters necessitate a comprehensive overview on their classifications, fabrication platforms, cellular/ macromolecular interactions, and eventually their prospective biomedical applications through illustrating the challenges and opportunities in different integrative medical and pharmaceutical fields. More particularly, an update on recent advances in zeolite-accommodated drug delivery and the prevalent challenges regarding these molecular sieves is to be presented. In conclusion, strategies to accelerate the translation of these porous materials from bench to bedside along with common overlooked physiological and pharmacological factors of zeolite nanoparticles are discussed and debated. Furthermore, for zeolite nanoparticles, it is a matter of crucial importance, in terms of biosafety and nanotoxicology, to appreciate the zeolite-bio interface once the zeolite nanoparticles are exposed to the biomacromolecules in biological media. We specifically shed light on interactions of zeolite nanoparticles with fibrinogen and amyloid beta which had been comprehensively investigated in our recent reports. Given the significance of zeolite nanoparticles' interactions with serum or interstitial proteins conferring them new biological identity, the preliminary approaches for deeper understanding of administration, distribution, metabolism and excretion of zeolite nanoparticles are elucidated.

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“…The cerium can act as a fantastic oxygen storage and release reservoir through a facile mutual transformation of Ce 4+ /Ce 3+ under oxidation-deoxidation conditions. [16][17][18][19] Likewise, MoO 3 -CeO 2 is an effective selective catalytic reduction catalyst to remove nitrogen oxides (NO x ). 20,21 Also, V-Mo(W)/TiO 2 is one of the most widely commercially used reduction catalyst.…”

Section: Introductionmentioning

confidence: 99%

β-Cyclodextrin supported MoO₃–CeO₂nanocomposite material as an efficient heterogeneous catalyst for degradation of phenol

Navgire¹,

Gogoi²,

Mallesham

et al. 2016

RSC Adv.

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Screening protocol for identifying inorganic oxides with anti-oxidant and pro-oxidant activity for biomedical, environmental and food preservation applications

Cited by 4 publications

References 28 publications

Nanosized microporous crystals: emerging applications

Nanosized microporous crystals: emerging applications

<p>Biomedical Applications of Zeolitic Nanoparticles, with an Emphasis on Medical Interventions</p>

β-Cyclodextrin supported MoO₃–CeO₂nanocomposite material as an efficient heterogeneous catalyst for degradation of phenol

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Screening protocol for identifying inorganic oxides with anti-oxidant and pro-oxidant activity for biomedical, environmental and food preservation applications

Cited by 4 publications

References 28 publications

Nanosized microporous crystals: emerging applications

Nanosized microporous crystals: emerging applications

<p>Biomedical Applications of Zeolitic Nanoparticles, with an Emphasis on Medical Interventions</p>

β-Cyclodextrin supported MoO3–CeO2nanocomposite material as an efficient heterogeneous catalyst for degradation of phenol

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β-Cyclodextrin supported MoO₃–CeO₂nanocomposite material as an efficient heterogeneous catalyst for degradation of phenol